関連論文

【2022】

TERT/BMI1-transgenic human dermal papilla cells enhance murine hair follicle formation in vivo

Mayumi Ikeda , Shigeharu Yabe , Masahiro Kiso , Naoko Ishiguro , Yuichiro Tsunemia , Hitoshi Okochi

Journal of Dermatological Science, Volume 106, Issue 2, May 2022, Pages 78-85

Bimodal expression of Wnt5a in the tooth germ: A comparative study using in situ hybridization and immunohistochemistry

Masataka Sunohara, Shigeru Morikawa, Naomi Asada, Kingo Suzuki

Journal of Dermatological Science, Volume 106, Issue 2, May 2022, Pages 78-85

Scientific Reports volume 12, Article number: 5389 (2022)

Shun Minatoguchi, Shoji Saito, Kazuhiro Furuhashi, Yuriko Sawa, Masaki Okazaki, Yuko Shimamura, Ahmad Baseer Kaihan, Yusaku Hashimoto, Yoshinari Yasuda, Akitoshi Hara, Yasuyuki Mizutani, Ryota Ando, Noritoshi Kato, Takuji Ishimoto, Naotake Tsuboi, Nobutoshi Esaki, Makoto Matsuyama, Yukihiro Shiraki, Hiroki Kobayashi, Naoya Asai, Atsushi Enomoto & Shoichi Maruyama

Scientific Reports volume 12, Article number: 5389 (2022)

Expression and localisation of MUC1 modi

Takanori Sugiura, Kazuhiko Hashimoto, Kazutaka Kikuta, Ukei Anazawa, Takeshi Nomura, Akihiko Kameyama

Research Square

Morphological study of subepithelial connective tissue and capillaries in the palatal gingiva of the maxillary first molar in obese type 2

Yoichi SUMI , Tatsuya KAMIMURA, Nobutaka OKUSA, Isumi TODA, Mamoru UEMURA

J Osaka Dent Univ 2022 (October); 56 (2): 151−160

Periosteal stem cells control growth plate stem cells during postnatal skeletal growth

Masayuki Tsukasaki, Noriko Komatsu, Takako Negishi-Koga, Nam Cong-Nhat Huynh, Ryunosuke Muro, Yutaro Ando, Yuka Seki, Asuka Terashima, Warunee Pluemsakunthai, Takeshi Nitta, Takashi Nakamura, Tomoki Nakashima, Shinsuke Ohba, Haruhiko Akiyama, Kazuo Okamoto, Roland Baron & Hiroshi Takayanagi

Nature Communications volume 13, Article number: 4166 (2022)

Identification of motilin in Japanese fire bellied newt

Mio Matsumoto, Shota Takemi, Takafumi Sakai, Ichiro Sakata

General and Comparative Endocrinology, Volumes 323–324, 1 July 2022, 11403

Dendritic distribution of CDK5 mRNA and p35 mRNA, and a glutamate-responsive increase of CDK5/p25 complex contribute to tau hyperphosphorylation

Toru Tanaka, Sachiyo Ohashi, Akihiko Takashima, Shunsuke Kobayashi

Biochimica et Biophysica Acta (BBA) – General Subjects, Volume 1866, Issue 7, July 2022, 130135

Xenogeneic-Free Human Intestinal Organoids for Assessing Intestinal Nutrient Absorption

Makoto Inoue, Yuichi Tanaka, Sakiko Matsushita, Yuri Shimozaki, Hirohito Ayame and Hidenori Akutsu

Nutrients 2022, 14, 438.

Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells

Gen Nishikawa, Kenji Kawada, Keita Hanada, Hisatsugu Maekawa, Yoshiro Itatani, Hiroyuki Miyoshi, Makoto Mark Taketo and Kazutaka Obama

Cells 2022, 11, 3273

Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis

Toshiyuki Ko, Seitaro Nomura, Shintaro Yamada, Kanna Fujita, Takanori Fujita, Masahiro Satoh, Chio Oka, Manami Katoh, Masamichi Ito, Mikako Katagiri, Tatsuro Sassa, Bo Zhang, Satoshi Hatsuse, Takanobu Yamada, Mutsuo Harada, Haruhiro Toko, Eisuke Amiya, Masaru Hatano, Osamu Kinoshita, Kan Nawata, Hiroyuki Abe, Tetsuo Ushiku, Minoru Ono, Masashi Ikeuchi, Hiroyuki Morita, Hiroyuki Aburatani & Issei Komuro

Nature Communications volume 13, Article number: 3275 (2022)

Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNA

Keiji Uehara, Toshimasa Harumoto, Asana Makino, Yasuo Koda, Junko Iwano, Yasuhiro Suzuki, Mari Tanigawa, Hiroto Iwai, Kana Asano, Kana Kurihara, Akinori Hamaguchi, Hiroshi Kodaira, Toshiyuki Atsumi, Yoji Yamada, Kazuma Tomizuka

Nucleic Acids Research, Volume 50, Issue 9, 20 May 2022, Pages 4840–4859

Lithium carbonate accelerates the healing of periapical periodontitis

Shousaku Itoh, Takumi Kagioka, Mai Hue, Makoto Abe, Mikako Hayashi

Research Square

Bacterial invasion into the epidermis of rats with sodium lauryl sulphate-irritated skin increases damage and induces incontinence-associated dermatitis

Sofoklis Koudounas, Takeo Minematsu, Yuko Mugita, Ayano Nakai, Hiromi Tobe, Chihiro Takizawa, Mao Kunimitsu, Gojiro Nakagami, Hiromi Sanada

Int Wound J. 2023;20:191–200

Testicular Hypoplasia with Normal Fertility in Neudesin-Knockout Mice

Hiroshi Hasegawa , Mari Kondo, Kei Nakayama, Tomoko Okuno, Nobuyuki Itoh, Morichika Konishi

Biol. Pharm. Bull. 45, 1791–1797 (2022)

Establishment of experimental salivary gland cancer models using organoid culture and patient-derived xenografting

Yoshihiro Aizawa, Kentaro Takada, Jun Aoyama, Daisuke Sano, Shoji Yamanaka, Masahide Seki, Yuta Kuze, Jordan A. Ramilowski, Ryo Okuda, Yasuharu Ueno, Yusuke Nojima, Yoshiaki Inayama, Hiromitsu Hatakeyama, Takashi Hatano, Hideaki Takahashi, Goshi Nishimura, Satoshi Fujii, Yutaka Suzuki, Hideki Taniguchi & Nobuhiko Oridate

Cellular Oncology volume 46, pages 409–421 (2023)

Two independent modes of kidney stone suppression achieved by AIM/CD5L and KIM-1

Kyohei Matsuura, Natsumi Maehara, Aika Hirota, Ayaka Eguchi, Keisuke Yasuda, Kaori Taniguchi, Akemi Nishijima, Nobuyuki Matsuhashi, Yoshiyuki Shiga, Rumi Ishii, Yasuhiro Iguchi, Kazunari Tanabe, Satoko Arai & Toru Miyazaki

Communications Biology volume 5, Article number: 783 (2022)

FE65 in breast cancer and its clinicopathological significance

Junyao Xu, Erina Iwabuchi, Yasuhiro Miki, Ayako Kanai, Takanori Ishida & Hironobu Sasano

Breast Cancer volume 29, pages 144–155 (2022)

Prediction of sex-determination mechanisms in avian primordial germ cells using RNA-seq analysis

Kennosuke Ichikawa, Yoshiaki Nakamura,Hidemasa Bono, Ryo Ezaki, Mei Matsuzaki, Hiroyuki Horiuchi

Scientific Reports doi: 10.1038/s41598-022-17726-7

H2 Inhibits the Formation of Neutrophil Extracellular Traps

Kohsuke Shirakawa, Eiji Kobayashi, Genki Ichihara, Hiroki Kitakata, Yoshinori Katsumata, Kazuhisa Sugai, Yoji Hakamata, Motoaki Sano

ACC: Basic to Translational Science, Volume 7, Issue 2, February 2022, Pages 146-161

Characterization of morphological alterations in micropapillary adenocarcinoma of the lung using an established cell line

Dai Sonoda, Koki Kamizaki, Yukiko Matsuo, Kana Aruga, Masashi Mikubo, Keishi Yamashita, Michiru Nishita, Yasuhiro Minami, Yukitoshi Satoh

ONCOLOGY REPORTS 47: 19, 2022

Immunohistochemistry-Based Fluorescent Nanoparticle Assay for Determination of Antibody Binding Capacity and Its Correlation with Flow Cytometry Analysis

Atsuro Tatsumi, Keisuke Morichika, Joseph Krueger & Hiroyuki Yokota

Analytical Letters

Lansoprazole and zoledronate delays hard tissue healing of tooth extraction sockets in dexamethasone-treated mice

Reina Yoshioka, Yuichi Mine, Masato Kaku, Hiroki Nikawa, Takeshi Murayama

Biomedicine & Pharmacotherapy, Volume 150, June 2022, 112991

Lattice-patterned collagen fibers and their dynamics in axolotl skin regeneration

Rena Kashimoto, Saya Furukawa, Sakiya Yamamoto, Yasuhiro Kamei, Joe Sakamoto, Shigenori Nonaka, Tomonobu M. Watanabe, Tatsuya Sakamoto, Hirotaka Sakamoto, Akira Satoh

Scientific Reports, (2022) 12:13528

Establishment and characterization of NCC-MPNST6-C1: a novel patient-derived cell line of malignant peripheral nerve sheath

Yooksil Sin, Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Takuya Ono, Taro Akiyama, Fumihiko Nakatani, Jun Sugaya, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

Human Cell volume 35, pages 400–407 (2022)

Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cance

Sadanori Watanabe, Akitada Yogo, Tsuguteru Otsubo, Hiroki Umehara, Jun Oishi, Toru Kodo, Toshihiko Masui, Shigeo Takaishi,

BMC Cancer volume 22, Article number: 489 (2022)

Establishment and characterization of NCC‑DMM1‑C1, a novel patient‑derived cell line of desmoplastic malignant pleural mesothelioma

Rei Noguchi, Yuki Yoshimatsu, Takuya Ono, Akane Sei, Noriko Motoi, Yasushi Yatabe, Yukihiro Yoshida, Shunichi Watanabe,

ONCOLOGY LETTERS 23: 64, 2022

Estrogen-Inducible LncRNA Kunik Functions as a Modulator for Estrogen Receptor Signaling in Endocrine-Resistant Breast Cancer

Kuniko Horie, Kiyoshi Takagi, Toshihiko Takeiwa, Yuichi Mitobe, Hidetaka Kawabata, Takashi Suzuki, Kazuhiro Ikeda and Satoshi Inoue

Cells 2022, 11(22), 3610

Puromycin-based purification of cells with high expression of the cytochrome P450 CYP3A4 gene from a patient with drug-induced liver injury (DILI)

Shoko Miyata, Noriaki Saku, Saeko Akiyama, Palaksha Kanive Javaregowda, Kenta Ite, Nagisa Takashima, Masashi Toyoda, Kei Yura,

Stem Cell Research & Therapy volume 13, Article number: 6 (2022)

Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma

Yasunao Numata, Noriyuki Akutsu, Keisuke Ishigami, Hideyuki Koide, Kohei Wagatsuma, Masayo Motoya, Shigeru Sasaki, Hiroshi Nakase

Biochemistry and Biophysics Reports, Volume 30, July 2022, 101270

Experimental models of salivary gland cancer established using organoid culture and patient-derived xenografting

Yoshihiro Aizawa, Kentaro Takada, Jun Aoyama, Daisuke Sano, Shoji Yamanaka, Masahide Seki, Yuta Kuze, Jordan A. Ramilowski, Ryo Okuda, Yasuharu Ueno, Yusuke Nojima, Yoshiaki Inayama, Hiromitsu Hatakeyama, Takashi Hatano, Hideaki Takahashi, Goshi Nishimura, Satoshi Fujii, Yutaka Suzuki, Hideki Taniguchi, Nobuhiko Oridate

Research Square

Establishment and characterization of NCC-UPS3-C1: a novel patient-derived cell line of undifferentiated pleomorphic sarcoma

Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Taro Akiyama, Jun Sugaya, Fumihiko Nakatani, Naoki Kojima, Akihiko Yoshida, Seiji Ohtori, Akira Kawai & Tadashi Kondo

Human Cell volume 35, pages 384–391 (2022)

Establishment and characterization of the NCC-GCTB4-C1 cell line: a novel patient-derived cell line from giant cell tumor of bone

Takuya Ono, Rei Noguchi, Yuki Yoshimatsu, Ryuto Tsuchiya, Yooksil Sin, Rumi Nakagawa, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta & Tadashi Kondo

Human Cell volume 35, pages 392–399 (2022)

Internalization and Decrease of Duodenal DMT1 Involved in Transient Suppression of Iron Uptake in Short-Acting Mucosal Block

Anna Arita, Ichiro Kita & Shoko Shinoda

Biological Trace Element Research volume 200, pages 4795–4806 (2022)

Close Association between Altered Urine–Urothelium Barrier and Tertiary Lymphoid Structure Formation in the Renal Pelvis during Nephritis

Osamu Ichii, Marina Hosotani , Md Abdul Masum, Taro Horino, Yuki Otani, Takashi Namba, Teppei Nakamura, Elewa Yaser Hosny Ali, Yasuhiro Kon

J Am Soc Nephrol. 2022 Jan; 33(1): 88–107.

Generation of four iPSC lines from a family harboring a 1p36–35 haplotype linked with bipolar disorder and recurrent depressive disorder: Three-generation patients and a healthy sibling

Gakuya Takamatsu, Yoko Manome, Jun-Seok Lee, Kanako Toyama, Tomoko Hayakawa, Chikako Hara-Miyauchi, Minami Hasegawa-Ogawa, Chiaki Katagiri, Tsuyoshi Kondo, Hirotaka James Okano, Masayuki Matsushita

Stem Cell Research, Volume 64, October 2022, 102915

An efficient procedure for the recovery of DNA from formalin-fixed paraffin-embedded tissue sections

Utako Oba, Kenichi Kohashi, Yuhei Sangatsuda, Yoshinao Oda, Koh-Hei Sonoda, Shouichi Ohga, Koji Yoshimoto, Yasuhito Arai, Shinichi Yachida, Tatsuhiro Shibata, Takashi Ito, Fumihito Miura

Biology Methods and Protocols, Volume 7, Issue 1, 2022, bpac014

      • 【2021】

        AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke

        Natsumi Maehara, Kaori Taniguchi, Ami Okuno, Hideaki Ando, Aika Hirota, Zhiheng Li, Ching-Ting Wang, Satoko Arai, Toru Miyazaki

        CELL Roports Volume 36, Issue 11, 14 September 2021, 109693

        High salt exacerbates acute kidney injury by disturbing the activation of CD5L/apoptosis inhibitor of macrophage (AIM) protein

        Ching-Ting Wang, Tetsushi Tezuka, Naoki Takeda, Kimi Araki, Satoko Arai , Toru Miyazaki

        PLoS ONE 16(11): e0260449.

        Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation

        Sau Yee Kok, Hiroko Oshima, Kei Takahashi, Mizuho Nakayama, Kazuhiro Murakami, Hiroki R. Ueda, Kohei Miyazono & Masanobu Oshima

        Nature Communications volume 12, Article number: 863 (2021)

        Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine

        Kazuhiro Hada, Bolati Wulaer, Taku Nagai, Norimichi Itoh, Masahito Sawahata, Akira Sobue, Hiroyuki Mizoguchi, Daisuke Mori, Itaru Kushima, Toshitaka Nabeshima, Norio Ozaki
        and Kiyofumi Yamada

        Molecular Brain volume 14, Article number: 21 (2021)

        Development of Prediction Model Including MicroRNA Expression for Sentinel Lymph Node Metastasis in ER-Positive and HER2-Negative Breast Cancer

        Jun Okuno, Tomohiro Miyake, Yoshiaki Sota, Tomonori Tanei, Naofumi Kagara, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim & Shinzaburo Noguchi

        Annals of Surgical Oncology volume 28, pages 310–319 (2021)

        Claudin-7 in keratinocytes is downregulated by the inhibition of HMG-CoA reductase and is highly expressed in the stratum granulosum of the psoriatic epidermis

        Sayaka Kuwatsuka, Yuta Koike, Yutaka Kuwatsuka, Toshifumi Yamaoka, Hiroyuki Murota

        Journal of Dermatological Science Volume 104, Issue 2, November 2021, Pages 132-137

        Immunohistochemical analysis of thrombomodulin expression in myocardial tissue from autopsy cases of ischemic heart disease

        Takeshi Kondo, Motonori Takahashi, Gentaro Yamasaki, Marie Sugimoto, Azumi Kuse, Mai Morichika, Kanako Nakagawa, Makoto Sakurada, Migiwa Asano, Yasuhiro Ueno

        Legal Medicine Volume 51, July 2021, 101897

        Characteristic expression of CGRP and osteogenic and vasculogenic markers in the proximal and distal regions of the rib during male mouse development

        Iori Sawada, Iwao Sato, Shinichi Kawata, Kenta Nagahori, Takuya Omotehara, Tomiko Yakura, Zhong-LianLi, Masahiro Itoh

        Annals of Anatomy – Anatomischer Anzeiger Volume 240, February 2022, 151883

        Reduced differentiation of intestinal epithelial cells in wasting marmoset syndrome

        Kimie NIIMI, Eiki TAKAHASHI

        J-STAGE Advance Published Date: 18 March 2021

        Hypermineralization of Hearing-Related Bones by a Specific Osteoblast Subtype

        Yukiko Kuroda, Katsuhiro Kawaai, Naoya Hatano, Yanlin Wu, Hidekazu Takano, Atsushi Momose, Takuya Ishimoto, Takayoshi Nakano, Paul Roschger, Stéphane Blouin, Koichi Matsuo

        Journal of Bone and Mineral Research, Vol. 36, No. 8, August 2021, pp 1535–1547.

        Prediction of single-cell mechanisms for disease progression in hypertrophic remodelling by a trans-omics approach

        Momoko Hamano, Seitaro Nomura, Midori Iida, Issei Komuro & Yoshihiro Yamanishi

        Scientific Reports volume 11, Article number: 8112 (2021)

        Comparison of CGRP distributions in the maxillary sinus and trigeminal ganglion between elderly dentulous and edentulous humans

        Hiroyuki Matsuda, Iwao Sato, Rieko Asaumi, Takuya Omotehara, Shinichi Kawata, Kenta Nagahori, Zhong-Lian Li, and Masahiro Itoh

        Eur J Histochem. 2021 Mar 24; 65(2): 3234.

        Anti-Ro/SSA Antibodies May Be Responsible for Cerebellar Degeneration in Sjogren’s Syndrome

        Syuichi Tetsuka, Tomohiro Suzuki, Tomoko Ogawa, Ritsuo Hashimoto, and Hiroyuki Kato

        J Clin Med Res. 2021 Feb; 13(2): 113–120.

        Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

        Takashi Toyama, Takayuki Hoshi, Takuya Noguchi, Yoshiro Saito, Atsushi Matsuzawa, Akira Naganuma & Gi-Wook Hwang

        Scientific Reports volume 11, Article number: 9832 (2021)

        Calcium-activated chloride channel is involved in the onset of diarrhea triggered by EGFR tyrosine kinase inhibitor treatment in rats

        Yumi Harada, Hitomi Sekine, Kunitsugu Kubota, Daichi Sadatomi, Seiichi Iizuka, Naoki Fujitsuka

        Biomedicine & Pharmacotherapy Volume 141, September 2021, 111860

        Protective Effects of Eicosapentaenoic Acid on the Glomerular Endothelium via Inhibition of EndMT in Diabetes

        Toshinori Yasuzawa, Tomomi Nakamura, Shigeru Ueshima, and Akira Mima

        Journal of Diabetes Research Volume 2021, Article ID 2182225, 13 pages

        Combination of Cisplatin and Irradiation Induces Immunogenic Cell Death and Potentiates Postirradiation Anti–PD-1 Treatment

        Hiroshi Fukushima, Soichiro Yoshida, Toshiki Kijima, Yuki Nakamura, Shohei Fukuda, Sho Uehara, Yosuke Yasuda, Hajime Tanaka, Minato Yokoyama, Yoh Matsuoka and Yasuhisa Fujii

        Int. J. Mol. Sci. 2021, 22(2), 535

        Development of a 3D Cell Culture System Using Amphiphilic Polydepsipeptides and Its Application to Hepatic Differentiation

        Junko Enomoto, Yukiko Toba, Haruka Yamazaki, Masaki Kanai, Hiroyuki Mizuguchi, and Hayato Matsui

        CS Appl. Bio Mater. 2021, 4, 9, 7290–7299

        Cryopreserved Spontaneous Spheroids from Compact Bone-Derived Mesenchymal Stromal Cells for Bone Tissue Engineering

        Hongwei Dong, Xianqi Li, Kai Chen, Ni Li, and Hideaki Kagami

        Tissue Engineering Part C: MethodsVol. 27, No. 4, 2021

        Establishment and characterization of NCC-MFS4-C1: a novel patient-derived cell line of myxofibrosarcoma

        Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Yooksil Sin, Takuya Ono, Jun Sugaya, Shintaro Iwata, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1911–1918 (2021)

        Establishment and characterization of NCC-MFS4-C1: a novel patient-derived cell line of myxofibrosarcoma

        Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Yooksil Sin, Takuya Ono, Jun Sugaya, Shintaro Iwata, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1911–1918 (2021)

        Establishment and characterization of NCC-MFS3-C1: a novel patient-derived cell line of myxofibrosarcoma

        Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Akane Sei, Fumitaka Takeshita, Jun Sugaya, Shintaro Iwata, Akihiko Yoshida, Seiji Ohtori, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1266–1273 (2021)

        Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells

        Akiko Tanuma-Takahashi, Momoko Inoue, Kazuhiro Kajiwara, Ryo Takagi, Ayumi Yamaguchi, Osamu Samura, Hidenori Akutsu, Haruhiko Sago, Tohru Kiyono, Aikou Okamoto & Akihiro Umezawa

        Stem Cell Research & Therapy volume 12, Article number: 476 (2021)

        Stem cell therapy for skin regeneration using mesenchymal stem cells derived from the progeroid Werner syndrome-specific iPS cells

        Shinichiro Funayama, Hisaya Kato, Hiyori Kaneko, Kentaro Kosaka, Daisuke Sawada, Aki Takada-Watanabe, Takuya Minamizuka, Yusuke Baba, Masaya Koshizaka, Akira Shimamoto, Yasuo Ouchi, Atsushi Iwama, Yusuke Endo, Naoya Takayama, Koji Eto, Yoshiro Maezawa, Koutaro Yokote

        bioRxiv

        Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling

        Yutaka Endo, Mao Fujimoto, Nanako Ito, Yoriko Takahashi, Minoru Kitago, Masahiro Gotoh, Nobuyoshi Hiraoka, Teruhiko Yoshida, Yuko Kitagawa, Yae Kanai & Eri Arai

        Journal of Cancer Research and Clinical Oncology volume 147, pages 1341–1354 (2021)

        Novel Preclinical Human Salivary Gland Cancer Models Established Using Organoid Culture And Patient-Derived Xenografting

        Aizawa Y, Takada K, Aoyama J, Sano D, Yamanaka S, Seki M, Kuze Y, Ramilowski J, Okuda R, Ueno Y, Nojima Y, Inayama Y, Hatakeyama H, Hatano T, Takahashi H, Nishimura G, Fujii S, Suzuki Y, Taniguchi H, Oridate N

        Research Square, 03 Sep 2021

        Establishment and characterization of NCC-ssRMS2-C1: a novel patient-derived cell line of spindle cell/sclerosing

        Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Akane Sei, Fumitaka Takeshita, Jun Sugaya, Fumihiko Nakatani, Akihiko Yoshida, Seiji Ohtori, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1569–1578 (2021)

        Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas

        Hiroyuki Tomita, Kaori Tanaka, Akihiro Hirata, Hideshi Okada, HisashiImai, Yohei Shirakami, Kotaro Ohnishi, Shigeyuki Sugie, Hitomi Aoki, Yuichiro Hatano, Kei Noguchi, Tomohiro Kanayama, AyumiNiwa, Natsuko Suzui, Tatsuhiko Miyazaki, Takuj iTanaka, Haruhiko Akiyama. Masahito Shimizu, Kazuhiro Yoshida, Akira Hara

        Cell Reports
        Volume 34, Issue 8, 23 February 2021, 108772

        Establishment and characterization of the NCC-GCTB4-C1 cell line: a novel patient-derived cell line from giant cell tumor of bone

        Takuya Ono, Rei Noguchi, Yuki Yoshimatsu, Ryuto Tsuchiya, Yooksil Sin, Rumi Nakagawa, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka

        Human Cell volume 35, pages 392–399 (2022)

        Establishment and characterization of NCC-LGFMS1-C1: a novel patient-derived cell line of low-grade fibromyxoid sarcoma

        Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Ryuto Tsuchiya, Takuya Ono, Akane Sei, Jun Sugaya, Shintaro Iwata, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1919–1928 (2021)

        Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration

        A. Osada, I. Matsumoto, N. Mikami, A. Ohyama, I. Kurata, Y. Kondo, H. Tsuboi, A. Ishigami, Y. Sano, T. Arai, N. Ise, T. Sumida

        Clinical & Experimental Immunology Volume203, Issue3 March 2021 Pages 385-399

        Establishment and characterization of NCC-DDLPS1-C1: a novel patient-derived cell line of dedifferentiated liposarcoma

        Rei Noguchi, Yuki Yoshimatsu, Takuya Ono, Akane Sei, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta & Tadashi Kondo

        Human Cell volume 34, pages 688–697 (2021)

        Establishment and characterization of novel patient-derived cell lines from giant cell tumor of bone

        Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Takuya Ono, Yooksil Sin, Sei Akane, Jun Sugaya, Tomoaki Mori, Suguru Fukushima, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1899–1910 (2021)

        Establishment and characterization of NCC-SS4-C1: a novel patient-derived cell line of synovial sarcoma

        Rei Noguchi, Yuki Yoshimatsu, Takuya Ono, Akane Sei, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta & Tadashi Kondo

        Human Cell volume 34, pages 688–697 (2021)

        Analysis of the mylohyoid nerve in elderly Japanese cadavers for dental implant surgery

        Shintaro Koga, Iwao Sato, Zhong-Lian Li, Hidenobu Miyaso, Shinichi Kawata, Masahiro Itoh

        Clinical and Experimental Dental Reserch Volume7, Issue1 February 2021 Pages 20-32

        Relationship between lamellar sensory corpuscles distributed along the upper arm’s deep arteries and pulsating sensation of blood vessels

        Yoshiyuki Onishi, Haruka Hisato, Seishi Maeda, Yusuke Minato, Sachi Kuwahara-Otani, Hideshi Yagi

        Journal of Anatomy Volume239, Issue1 July 2021 Pages 101-110

        Identification of microRNAs responsive to shear loading in rat skin

        Wei-Jhen Hsu, Takeo Minematsu, Gojiro Nakagami, Sofoklis Koudounas, Sanai Tomida, Ayano Nakai, Mao Kunimitsu, Shiori Nitta, Hiromi Sanada

        Int Wound J. 2021;1–11.

        Establishment and characterization of NCC-LMS2-C1—a novel patient-derived cancer cell line of leiomyosarcoma

        Rei Noguchi, Yuki Yoshimatsu, Takuya Ono, Akane Sei, Kaoru Hirabayashi, Iwao Ozawa, Kazutaka Kikuta & Tadashi Kondo

        Human Cell volume 34, pages 279–288 (2021)

        Establishment and characterization of novel patient-derived cell lines from giant cell tumor of bone

        Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Takuya Ono, Yooksil Sin, Sei Akane, Jun Sugaya, Tomoaki Mori, Suguru Fukushima, Akihiko Yoshida, Akira Kawai & Tadashi Kondo

        Human Cell volume 34, pages 1899–1910 (2021)

        Viability of diffuse large B-cell lymphoma cells is regulated by kynurenine 3-monooxygenase activity

        Nanaka Morita Masato Hoshi Takeshi Hara Soranobu Ninomiya Taisuke Enoki Misao Yoneda Hisashi Tsurumi Kuniaki Saito

        ONCOLOGY LETTERS 22: 790, 2021

        Induction of mucosal immunity by pulmonary administration of a cell-targeting nanoparticle

        Tomoaki Kurosaki, Yuki Katafuchi, Junya Hashizume, Hitomi Harasawa, Hiroo Nakagawa, Mikiro Nakashima, Tadahiro Nakamura, Chikamasa Yamashita, Hitoshi Sasaki & Yukinobu Kodama

        Drug Delivery, 28:1, 1585-1593

        Pathogenic roles and therapeutic potential of the CCL8–CCR8 axis in a murine model of IgG4-related sialadenitis

        Honda F, Tsuboi H, Ono Y, Abe S, Takahashi H, Ito K, Yamada K, Kawano M, Kondo Y, Asano K, Tanaka M, Malissen M, Malissen B, Matsumoto I, Sumida T

        Research Square, 21 Apr 2021

        Core-shell hydrogel microfiber-expanded pluripotent stem cell-derived lung progenitors applicable to lung reconstruction in vivo

        Satoshi Ikeo, Yuki Yamamoto, Kazuhiro Ikeda, Naoyuki Sone, Yohei Korogi, Lucia Tomiyama, Hisako Matsumoto, Toyohiro Hirai, Masatoshi Hagiwara, Shimpei Gotoh

        Biomaterials Volume 276, September 2021, 121031

        Vagus nerve stimulation modulates arachidonic acid production in the mesenteric lymph following intestinal ischemia-reperfusion injury

        Keita Nakatsutsumi 1 , Koji Morishita, Masayuki Yagi, Sanae Doki, Arisa Watanabe, Nahoko Ikegami, Testuyuki Kobayashi, Mitsuaki Kojima, Atsushi Senda, Kouhei Yamamoto, Junichi Aiboshi, Raul Coimbra, Yasuhiro Otomo

        J Trauma Acute Care Surg . 2021 Oct 1;91(4):700-707

        Establishment and Characterization of NCC-DDLPS4-C1: A Novel Patient-Derived Cell Line of Dedifferentiated Liposarcoma

        Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Taro Akiyama, Takeshi Hirose, Shintaro Iwata, Akihiko Yoshida, Seiji Ohtori, Akira Kawai and Tadashi Kondo

        J. Pers. Med. 2021, 11(11), 1075

        Drug metabolism activity is a Critical Intrinsic Selector for Hepatocytes to elongate cell lifespan by using a cell-killing antibiotic

        Saeko Akiyama, Noriaki Saku, Shoko Miyata, Kenta Ite, Masashi Toyoda, Tohru Kimura, Masahiko Kuroda, Atsuko Nakazawa, Mureo Kasahara, Hidenori Nonaka, Akihide Kamiya, Tohru Kiyono, Toru Kobayshi, Yasufumi Murakami, Akihiro Umezawa

        bioRxiv, 19 Apr 2021

        Depletion of PD-1 or PD-L1 did not affect the mortality of mice infected with Mycobacterium avium

        Masayuki Nakajima, Masashi Matsuyama, Mio Kawaguchi, Sosuke Matsumura, Takumi Kiwamoto, Yosuke Matsuno, Yuko Morishima, Kazufumi Yoshida, Mingma Thsering Sherpa, Kai Yazaki, Ryota Tanaka, Naoko Okiyama, Masafumi Muratani, Yukio Ishii & Nobuyuki Hizawa

        Scientific Reports volume 11, Article number: 18008 (2021)

        Establishment of in vitro 3D spheroid cell cultivation from human gynecologic cancer tissues

        Haruka Ueda, Yutaro Mori, Kaoru Yamawaki, Tatsuya Ishiguro, Hirokazu Ohata, Ai Sato, Kentaro Sugino, Nozomi Yachida, Manako Yamaguchi, Kazuaki Suda, Ryo Tamura, Kosuke Yoshihara, Koji Okamoto, Takayuki Enomoto

        STAR Protocols Volume 2, Issue 1, 19 March 2021, 100354

        Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion

        Akikazu Harada, Shinji Matsumoto, Yoshiaki Yasumizu, Kensaku Shojima, Toshiyuki Akama, Hidetoshi Eguchi, Akira Kikuchi

        life . 2021 Sep 30;10:e66721

        Kras activation in endometrial organoids drives cellular transformation and epithelial-mesenchymal transition

        Yoshiaki Maru, Naotake Tanaka, Yasutoshi Tatsumi, Yuki Nakamura, Makiko Itami & Yoshitaka Hippo

        Oncogenesis volume 10, Article number: 46 (2021)

        Royal Jelly Protects against Epidermal Stress through Upregulation of the NQO1 Expression

        Nobuaki Okumura, Takashi Ito, Tomomi Degawa, Mariko Moriyama and Hiroyuki Moriyama

        Int. J. Mol. Sci. 2021, 22(23), 12973

        Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function

        Momotaro Kawai, Kent Imaizumi, Mitsuru Ishikawa, Shinsuke Shibata, Munehisa Shinozaki, Takahiro Shibata, Shogo Hashimoto, Takahiro Kitagawa, Kentaro Ago, Keita Kajikawa, Reo Shibata, Yasuhiro Kamata, Junichi Ushiba, Keisuke Koga, Hidemasa Furue, Morio Matsumoto, Masaya Nakamura, Narihito Nagoshi, Hideyuki Okano

        Cell Reports Volume 37, Issue 8, 23 November 2021, 110019

        Clinicopathological and Preclinical Patient-Derived Model Studies Define High Expression of NRN1 as a Diagnostic and Therapeutic Target for Clear Cell Renal Cell Carcinoma

        Shuhei Kamada, Kazuhiro Ikeda, Takashi Suzuki, Wataru Sato, Sachi Kitayama, Satoru Kawakami, Tomohiko Ichikawa, Kuniko Horie, and Satoshi Inoue

        Front Oncol. 2021; 11: 758503.

        Functional inhibition of cancer stemness-related protein DPP4 rescues tyrosine kinase inhibitor resistance in renal cell carcinoma

        Shuhei Kamada, Takeshi Namekawa, Kazuhiro Ikeda, Takashi Suzuki, Makoto Kagawa, Hideki Takeshita, Akihiro Yano, Koji Okamoto, Tomohiko Ichikawa, Kuniko Horie-Inoue, Satoru Kawakami & Satoshi Inoue

        Oncogene volume 40, pages 3899–3913 (2021)

        CD82 is a marker to isolate β cell precursors from human iPS cells and plays a role for the maturation of β cells

        Ami Watanabe, Anna Tanaka, Chizuko Koga, Masahito Matsumoto, Yasushi Okazaki, Tatsuya Kin & Atsushi Miyajima

        Scientific Reports volume 11, Article number: 9530 (2021)

        Bone Tissue Response to Different Grown Crystal Batches of Octacalcium Phosphate in Rat Long Bone Intramedullary Canal Area

        Yukari Shiwaku, Ryo Hamai, Shinichi Sato, Susumu Sakai, Kaori Tsuchiya, Kazuyoshi Baba, Tetsu Takahashi and Osamu Suzuki

        Int. J. Mol. Sci. 2021, 22(18), 9770

        Tumor necroptosis is correlated with a favorable immune cell signature and programmed death-ligand 1 expression in cholangiocarcinoma

        Thanpisit Lomphithak, Perawatt Akara-amornthum, Keigo Murakami, Masatoshi Hashimoto, Hajime Usubuchi, Erina Iwabuchi, Michiaki Unno, Zhenyu Cai, Hironobu Sasano & Siriporn Jitkaew

        Scientific Reports volume 11, Article number: 11743 (2021)

        Plasticity of Neural Connections Underlying Oxytocin-mediated Parental Behaviors of Male Mice

        Kengo Inada, Mitsue Hagihara, Kazuko Tsujimoto, Takaya Abe, View ORCID ProfileAyumu Konno, View ORCID ProfileHirokazu Hirai, View ORCID ProfileHiroshi Kiyonari, View ORCID ProfileKazunari Miyamichi

        bioRxiv, 21 Oct 2021

        Recording and neural circuit-based manipulation of the maternal oxytocin pulses in mice

        Hiroko Yukinaga, Mitsue Hagihara, Kazuko Tsujimoto, Hsiao-Ling Chiang, View ORCID ProfileShigeki Kato, View ORCID ProfileKazuto Kobayashi, View ORCID ProfileKazunari Miyamichi

        bioRxiv, 26 Jul 2021

        Recruitment of KRAS downstream target ARL4C to membrane protrusions accelerates pancreatic cancer cell invasion

        Akikazu Harada, Shinji Matsumoto, View ORCID ProfileYoshiaki Yasumizu, Toshiyuki Akama, Hidetoshi Eguchi, View ORCID ProfileAkira Kikuchi

        bioRxiv, 24 Feb 2021

        Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening

        Toshiki Ebisudani, Shinya Sugimoto, Kei Haga, Akifumi Mitsuishi, ReikoTakai-Todaka, Masayuki Fujii, Kohta Toshimitsu, Junko Hamamoto, Kai Sugihara, Tomoyuki Hishida, Hisao Asamura, Koichi Fukunaga, Hiroyuki Yasuda, Kazuhiko Katayama, Toshiro Sato

        Cell Reports Volume 35, Issue 10, 8 June 2021, 109218

        【2020】

        Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine

        Kazuhiro Hada, Bolati Wulaer, Taku Nagai, Norimichi Itoh, Masahito Sawahata, Akira Sobue, Hiroyuki Mizoguchi, Daisuke Mori, Itaru Kushima, Toshitaka Nabeshima, Norio Ozaki and Kiyofumi Yamada

        Molecular Brain volume 14, Article number: 21 (2021)

        Enhanced junctional epithelial permeability in TRPV4-deficient mice

        Tomoko Kitsuki, Reiko U. Yoshimoto, Reona Aijima, Junko Hatakeyama, Ai-Lin Cao, Jing-Qi Zhang, Yasuyoshi Ohsaki, Yoshihide Mori, Mizuho A. Kido

        J Periodontal Res. 2020 Jan;55(1):51-60

        Extracellular vesicles microRNA analysis in type 1 autoimmune pancreatitis: Increased expression of microRNA-21

        Koh Nakamaru , Takashi Tomiyama , Sanshiro Kobayashi , Manami Ikemune , Satoshi Tsukuda , Takashi Ito , Toshihiro Tanaka , Takashi Yamaguchi , Yugo Ando , Tsukasa Ikeura , Toshiro Fukui , Akiyoshi Nishio , Makoto Takaoka , Kazushige Uchida , Patrick S C Leung , M E Gershwin , Kazuichi Okazaki

        Pancreatology. 2020 Apr;20(3):318-324

        CANT1 deficiency in a mouse model of Desbuquois dysplasia impairs glycosaminoglycan synthesis and chondrocyte differentiation in growth plate cartilage

        Kazuki Kodama, Hiroaki Takahashi, Nobuyasu Oiji, Kenta Nakano, Tadashi Okamura, Kimie Niimi, Eiki Takahashi, Long Guo, Shiro Ikegawa, Tatsuya Furuichi

        FEBS Open Bio. 2020 Jun;10(6):1096-1103

        Experience with Large Panel Next-generation Sequencing in Patients with Advanced Solid Cancers at Juntendo University Hospital

        TAKUO HAYASHI, SHUNSUKE KATO

        Juntendo Medical Journal 2020. 66(5), 392-402

        A novel Asfarvirus-like virus identified as a potential cause of mass mortality of abalone

        Tomomasa Matsuyama, Tomokazu Takano, Issei Nishiki, Atushi Fujiwara, Ikunari Kiryu, Mari Inada, Takamitsu Sakai, Sachiko

        Sci Rep. 2020 May 15;10(1):8378

        Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas

        Kimiko Inoue, Narumi Ogonuki, Satoshi Kamimura, Hiroki Inoue, Shogo Matoba, Michiko Hirose, Arata Honda, Kento Miura, Masashi Hada, Ayumi Hasegawa, Naomi Watanabe, Yukiko Dodo, Keiji Mochida & Atsuo Ogura

        Nat Commun. 2020 May 1;11(1):2150

        RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis

        Erika Sugisawa , Yasunori Takayama , Naoki Takemura , Takeshi Kondo , Shigetsugu Hatakeyama , Yutaro Kumagai , Masataka

        Cell. 2020 Aug 6;182(3):609-624

        ISG20 is overexpressed in clinically relevant radioresistant oral cancer cells

        Hitoshi Miyashita, Motoi Fukumoto, Yoshikazu Kuwahara, Tetsu Takahashi, Manabu Fukumoto

        Int J Clin Exp Pathol. 2020 Jul 1;13(7):1633-1639

        Infertility Caused by Inefficient Apoptotic Germ Cell Clearance in Xkr8-Deficient Male Mice

        Yahiro Yamashita, Chigure Suzuki, Yasuo Uchiyama, Shigekazu Nagata

        Mol Cell Biol. 2020 Jan 16;40(3):e00402-19

        ASK1 promotes uterine inflammation leading to pathological preterm birth

        Midori Yoshikawa, Takayuki Iriyama, Kensuke Suzuki, Seisuke Sayama, Tetsushi Tsuruga, Keiichi Kumasawa, Takeshi Nagamatsu, Kengo Homma, Isao Naguro, Yutaka Osuga, Hidenori Ichijo & Tomoyuki Fujii

        Sci Rep. 2020 Feb 5;10(1):1887

        Paternal restraint stress affects offspring metabolism via ATF-2 dependent mechanisms in Drosophila melanogaster germ cells

        Ki-Hyeon Seong, Nhung Hong Ly, Yuki Katou, Naoko Yokota, Ryuichiro Nakato, Shinnosuke Murakami, Akiyoshi Hirayama, Shinji Fukuda, Siu Kang, Tomoyoshi Soga, Katsuhiko Shirahige & Shunsuke Ishii

        Commun Biol. 2020 May 18;3(1):251

        Vulnerability to psychological stress-induced anorexia in female mice depends on blockade of ghrelin signal in nucleus tractus solitarius

        Chihiro Yamada, Seiichi Iizuka, Miwa Nahata, Tomohisa Hattori, Hiroshi Takeda

        Br J Pharmacol. 2020 Oct;177(20):4666-4682

        Precancerous Lesions and Liver Atrophy as Risk Factors for Hepatolithiasis-Related Death after Liver Resection for Hepatolithiasis

        Toru Miyazaki, Hiroji Shinkawa, Shigekazu Takemura, Shogo Tanaka, Ryosuke Amano, Kenjiro Kimura, Go Ohira, Kohei Nishio, Masahiko Kinoshita, Jun Tauchi, Atsushi Ishihara, Shimpei Eguchi, Daisuke Shirai, Takatsugu Yamamoto, Kenichi Wakasa, Norifumi Kawada, and Shoji Kubo1

        Asian Pac J Cancer Prev. 2020 Dec 1;21(12):3647-3654

        Deletion in the Cobalamin Synthetase W Domain–Containing Protein 1 Gene Is associated with Congenital Anomalies of the Kidney and Urinary Tract

        Shoichiro Kanda, Masaki Ohmuraya, Hiroyuki Akagawa, Shigeru Horita, Yasuhiro Yoshida, Naoto Kaneko, Noriko Sugawara, Kiyonobu Ishizuka, Kenichiro Miura, Yutaka Harita, Toshiyuki Yamamoto, Akira Oka, Kimi Araki, Toru Furukawa and Motoshi Hattori

        J Am Soc Nephrol. 2020 Jan;31(1):139-147

        KLF4 Regulates Goblet Cell Differentiation in BMI1+ Reserve Intestinal Stem Cell Lineage during Homeostasis

        Takahito Katano, Agnieszka B. Bialkowska, and Vincent W. Yang

        Int J Stem Cells. 2020 Nov 30;13(3):424-431

        Combination efficacy of pertuzumab and trastuzumab for trastuzumab emtansine-resistant cells exhibiting attenuated lysosomal trafficking or efflux pumps upregulation

        Yoriko Yamashita-Kashima, Sei Shu, Masahiro Osada, Takaaki Fujimura, Shigeki Yoshiura, Naoki Harada & Yasushi Yoshimura

        Int J Stem Cells. 2020 Nov 30;13(3):424-431

        Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma

        Masahiro Shimokawa, Tomoharu Yoshizumi, Shinji Itoh, Norifumi Iseda, Kazuhito Sakata, Kyohei Yugawa, Takeo Toshima, Noboru Harada, Toru Ikegami, Masaki Mori

        Cancer Sci. 2020 Apr;111(4):1228-1240

        Immunohistochemical study for relationship between vessel and lymphatic properties and tooth marks in human oral mucosa

        Toru Inomata, Yoko Miwa, Shinichi Kawata, Takuya Omotehara, Iwao Sato, and Masahiro Itoh

        Eur J Histochem. 2020 Feb 26;64(1):3095

        Olig2-Induced Semaphorin Expression Drives Corticospinal Axon Retraction After Spinal Cord Injury

        Masaki Ueno, Yuka Nakamura, Hiroshi Nakagawa, Jesse K Niehaus, Mari Maezawa, Zirong Gu, Atsushi Kumanogoh, Hirohide Takebayashi, Qing Richard Lu, Masahiko Takada, Yutaka Yoshida

        Cereb Cortex. 2020 Oct 1;30(11):5702-5716

        Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response

        Hiroaki Mashima , Rong Zhang , Tsuyoshi Kobayashi , Yuichiro Hagiya , Hirotake Tsukamoto , Tianyi Liu , Tatsuaki Iwama , Masateru Yamamoto , Chiahsuan Lin , Ryusuke Nakatsuka , Yuta Mishima , Noriko Watanabe , Takashi Yamada , Satoru Senju , Shin Kaneko , Alimjan Idiris , Tetsuya Nakatsura , Hideki Ohdan , Yasushi Uemura

        Oncoimmunology. 2020 Sep 6;9(1):1814620

        Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma

        Masahiro Shimokawa , Tomoharu Yoshizumi , Shinji Itoh , Norifumi Iseda , Kazuhito Sakata , Kyohei Yugawa , Takeo Toshima , Noboru Harada , Toru Ikegami , Masaki Mori

        Cancer Sci. 2020 Apr;111(4):1228-124

        ALDH1A1 in patient-derived bladder cancer spheroids activates retinoic acid signaling leading to TUBB3 overexpression and tumor progression

        Takeshi Namekawa, Kazuhiro Ikeda, Kuniko Horie-Inoue, Takashi Suzuki, Koji Okamoto, Tomohiko Ichikawa, Akihiro Yano, Satoru Kawakami, Satoshi Inoue

        Int J Cancer. 2020 Feb 15;146(4):1099-1113

        Good prognosis for follicular lymphoma with estrogen receptor α-positive follicular dendritic cells

        Rintaro Ohe, Hong-Xue Meng, Akane Yamada, Naing Ye Aung, Takanobu Kabasawa, Yuka Tamura, Aya Utsunomiya, Nobuyuki Tamazawa, Ichiro Kawamura, Takumi Kitaoka, Kazushi Suzuki, Ryo Yanagiya, Tomomi Toubai, Kenichi Ishizawa, Mitsunori Yamakawa

        Hematol Oncol. 2020 Aug;38(3):293-300

        Circulation of gut-preactivated naïve CD8+ T cells enhances antitumor immunity in B cell-defective mice

        Maryam Akrami , Rosemary Menzies , Kenji Chamoto , Michio Miyajima , Ryuji Suzuki , Hiroyuki Sato , Akiko Nishii , Michio Tomura , Sidonia Fagarasan , Tasuku Honjo

        Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23674-23683

        Rescue from Stx2-Producing E. coli-Associated Encephalopathy by Intravenous Injection of Muse Cells in NOD-SCID Mice

        Ryo Ozuru , Shohei Wakao , Takahiro Tsuji , Naoya Ohara , Takashi Matsuba , Muhammad Y Amuran , Junko Isobe , Morio Iino , Naoki Nishida , Sari Matsumoto , Kimiharu Iwadate , Noriko Konishi , Kaori Yasuda , Kosuke Tashiro , Misato Hida , Arisato Yadoiwa , Shinsuke Kato , Eijiro Yamashita , Sohkichi Matsumoto , Yoichi Kurozawa , Mari Dezawa , Jun Fujii

        Mol Ther. 2020 Jan 8;28(1):100-118

        DS-7080a, a Selective Anti-ROBO4 Antibody, Shows Anti-Angiogenic Efficacy with Distinctly Different Profiles from Anti-VEGF Agents

        Yoshitaka Isumi, Shinko Hayashi, Tatsuya Inoue, Yasushi Yoshigae, Toshiyuki Sato, Jun Hasegawa, Toshinori Agatsuma

        Transl Vis Sci Technol. 2020 Aug 5;9(9):7

        Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

        Shinsuke Nakazawa , Takatoshi Shimauchi , Atsuko Funakoshi , Masahiro Aoshima , Pawit Phadungsaksawasdi , Jun-Ichi Sakabe , Sanki Asakawa , Noriyasu Hirasawa , Taisuke Ito , Yoshiki Tokura

        Sci Rep. 2020 Sep 3;10(1):14559

        Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice

        Congyun Jin, Atsushi Yonezawa, Hiroki Yoshimatsu, Satoshi Imai, Madoka Koyanagi, Kaori Yamanishi, Shunsaku Nakagawa, Kotaro Itohara, Tomohiro Omura, Takayuki Nakagawa, Junya Nagai & Kazuo Matsubara

        Sci Rep. 2020 Oct 28;10(1):18443

        Expression and localisation of Rab44 in immune-related cells change during cell differentiation and stimulation

        Mitsuko Tokuhisa, Tomoko Kadowaki, Kohei Ogawa, Yu Yamaguchi, Mizuho A. Kido, Weiqi Gao, Masahiro Umeda & Takayuki Tsukuba

        Sci Rep. 2020 Jul 1;10(1):10728

        Neurofibromatosis type 1 associated with hypophosphatemic osteomalacia due to hypersecretion of fibroblast growth factor 23: a case report

        Takahiko Obo, Nobuyuki Koriyama, Akinori Tokito, Kazuma Ogiso & Yoshihiko Nishio

        J Med Case Rep. 2020 May 9;14(1):56

        Region- and neuronal-subtype-specific expression of Na,K-ATPase alpha and beta subunit isoforms in the mouse brain

        Koshi Murata, Tomoki Kinoshita, Tatsuya Ishikawa, Kazuki Kuroda, Minako Hoshi, Yugo Fukazawa

        J Comp Neurol. 2020 Nov 1;528(16):2654-2678

        Immortalization of human hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing

        Manami Nishiwaki, Masashi Toyoda, Yoshie Oishi, Seiichi Ishida, Shin-ichiro Horiuchi, Hatsune Makino-Itou, Tohru Kimura, Shin-ichi Ohno, Takashi Ohkura, Shin Enosawa, Hidenori Akutsu, Atsuko Nakazawa, Mureo Kasahara, Tohru Kiyono & Akihiro Umezawa

        Sci Rep. 2020 Oct 15;10(1):17503

        (Pro)renin receptor/ATP6AP2 is required for autophagy and regulates proliferation in lung adenocarcinoma cells

        Koji Ohba, Moe Endo, Shigemitsu Sato, Yurina Kashio-Yokota, Takuo Hirose, Kazuhiro Takahashi

        Genes Cells. 2020 Dec;25(12):782-795

        Organoid-based ex vivo reconstitution of Kras-driven pancreatic ductal carcinogenesis

        Tetsuya Matsuura, Yoshiaki Maru, Masashi Izumiya, Daisuke Hoshi, Shingo Kato, Masako Ochiai, Mika Hori, Shogo Yamamoto, Kenji Tatsuno, Toshio Imai, Hiroyuki Aburatani, Atsushi Nakajima, Yoshitaka Hippo

        Carcinogenesis. 2020 Jun 17;41(4):490-501

        Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages

        Kenta Maruyama , Hiroyasu Kidoya , Naoki Takemura , Erika Sugisawa , Osamu Takeuchi , Takeshi Kondo , Mohammed Mansour Abbas Eid , Hiroki Tanaka , Mikaël M Martino , Nobuyuki Takakura , Yasunori Takayama , Shizuo Akira , Alexis Vandenbon , Yutaro Kumagai

        Cell Rep. 2020 Jul 14;32(2):107906

        In vivo profiling of 2,3,7,8-tetrachlorodibenzo-p-dioxin–induced estrogenic/anti-estrogenic effects in female estrogen-responsive reporter transgenic mice

        Ichiro Yoshida , Keishi Ishida , Hiroshi Yoshikawa , Sho Kitamura , Youhei Hiromori , Yasushi Nishioka , Akiko Ido , Tomoki Kimura , Jun-Ichi Nishikawa , Jianying Hu , Hisamitsu Nagase , Tsuyoshi Nakanishi

        J Hazard Mater. 2020 Mar 5;385:121526

        The Fragility of Cryopreserved Insulin-producing Cells Differentiated from Adipose-tissue-derived Stem Cells

        Kazunori Tokuda , Tetsuya Ikemoto , Yu Saito , Katsuki Miyazaki , Shoko Yamashita , Shinichiro Yamada , Satoru Imura , Yuji Morine , Mitsuo Shimada

        Cell Transplant. Jan-Dec 2020;29:963689720954798

        The Role of Gut Microbiome in Psoriasis: Oral Administration of Staphylococcus aureus and Streptococcus danieliae Exacerbates Skin Inflammation of Imiquimod-Induced Psoriasis-Like Dermatitis

        Karin OkadaORCID, Yoshiaki Matsushima, Kento Mizutani and Keiichi Yamanaka

        Int J Mol Sci. 2020 May 7;21(9):3303

        Downregulation of the CCL2/CCR2 and CXCL10/CXCR3 axes contributes to antitumor effects in a mouse model of malignant glioma

        Kenji Shono, Izumi Yamaguchi, Yoshifumi Mizobuchi, Hiroshi Kagusa, Akiko Sumi, Toshitaka Fujihara, Kohei Nakajima, Keiko T. Kitazato, Kazuhito Matsuzaki, Hideyuki Saya & Yasushi Takagi

        Sci Rep. 2020 Sep 17;10(1):15286

        Establishment of fast-growing serum-free immortalised cells from Chinese hamster lung tissues for biopharmaceutical production

        Noriko Yamano-Adachi, Rintaro Arishima, Sukwattananipaat Puriwat & Takeshi Omasa

        Sci Rep. 2020 Oct 19;10(1):17612

        Establishment and Molecular Phenotyping of Organoids from the Squamocolumnar Junction Region of the Uterine Cervix

        Yoshiaki Maru , Akira Kawata, Ayumi Taguchi , Yoshiyuki Ishii, Satoshi Baba, Mayuyo Mori, Takeshi Nagamatsu, Katsutoshi Oda, Iwao Kukimoto, Yutaka Osuga, Tomoyuki Fujii and Yoshitaka Hippo

        Cancers (Basel). 2020 Mar 15;12(3):694

        Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d

        Takashi Semba , Ryo Sato , Akiyoshi Kasuga , Kentaro Suina , Tatsuhiro Shibata , Takashi Kohno , Makoto Suzuki , Hideyuki Saya , Yoshimi Arima

        Cancers (Basel). 2020 Dec 17;12(12):3805

        BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts

        Yuhei Yahiro, Shingo Maeda, Masato Morikawa, Daizo Koinuma, Go Jokoji, Toshiro Ijuin, Setsuro Komiya, Ryoichiro Kageyama, Kohei Miyazono & Noboru Taniguchi

        Bone Res. 2020 Sep 2;8(1):32

        Changes in subcellular structures and states of pumilio 1 regulate the translation of target Mad2 and cyclin B1 mRNAs

        Natsumi Takei , Yuki Takada , Shohei Kawamura , Keisuke Sato , Atsushi Saitoh , Jenny Bormann, Wai Shan Yuen , John Carroll, Tomoya Kotani

        J Cell Sci. 2020 Dec 11;133(23):jcs249128

        Follistatin expressed in mechanically-damaged salivary glands of male mice induces proliferation of CD49f+ cells

        A. Ikeda, T. Yamamoto, J. Mineshiba & S. Takashiba

        Sci Rep. 2020 Nov 17;10(1):19959

        Regulation of Chondrocyte Differentiation by Changing Intercellular Distances Using Type II Collagen Microfibers

        Jinyu Li, Naoko Sasaki, Keiji Itaka, Margo Terpstra, Riccardo Levato, and Michiya Matsusaki

        ACS Biomater Sci Eng. 2020 Oct 12;6(10):5711-5719

        Transient FOXO1 inhibition in pancreatic endoderm promotes the generation of NGN3+ endocrine precursors from human iPSCs

        Ben Sasaki , Shinji Uemoto , Yoshiya Kawaguchi

        Stem Cell Res. 2020 Apr;44:101754

        Vascularized cancer on a chip: The effect of perfusion on growth and drug delivery of tumor spheroid

        Yuji Nashimoto , Ryu Okada , Sanshiro Hanada , Yuichiro Arima , Koichi Nishiyama , Takashi Miura , Ryuji Yokokawa

        Biomaterials. 2020 Jan;229:119547

        Establishment and characterization of a novel alveolar rhabdomyosarcoma cell line, NCC-aRMS1-C1

        Yooksil Sin , Yuki Yoshimatsu , Rei Noguchi , Ryuto Tsuchiya , Akane Sei , Takuya Ono , Shunichi Toki , Eisuke Kobayashi , Ayumu Arakawa , Masanaka Sugiyama , Akihiko Yoshida , Akira Kawai , Tadashi Kondo

        Hum Cell. 2020 Oct;33(4):1311-1320

        Establishment and characterization of NCC-ASPS1-C1: a novel patient-derived cell line of alveolar soft-part sarcoma

        Yuki Yoshimatsu, Rei Noguchi, Ryuto Tsuchiya, Akane Sei, Jun Sugaya, Suguru Fukushima, Akihiko Yoshida, Akira Kawai & Tadashi

        Hum Cell. 2020 Oct;33(4):1302-1310

        A novel evaluation method for determining drug-induced hepatotoxicity using 3D bio-printed human liver tissue

        Izumi Ide, Eri Nagao, Sakura Kajiyama & Natsumi Mizoguchi

        Toxicol Mech Methods. 2020 Mar;30(3):189-196

        【2019】

        Visual arrestin modulates gene expression in the retinal pigment epithelium: Implications for homeostasis in the retina

        Natsuko Nagaoka, Takeshi Yoshida, Kejia Cao, Yuko Iwasaki, Ken-Ichi Nakahama, Ikuo Morita, Kyoko Ohno-Matsui

        Biochemistry and Biophysics Reports Volume 20, December 2019, 100680

        Distribution of the neuropeptide calcitonin gene-related peptide-α of tooth germ during formation of the mouse mandible

        Yuuki Maeda, Yoko Miwa, Iwao Sato

        Annals of Anatomy – Anatomischer Anzeiger Volume 221, January 2019, Pages 38-47

        Expression of apoptosis inhibitor of macrophages in tissue macrophages, leukocytes and vascular endothelial cells of dogs

        M.Uchida, K.Uchida, S.Maeda, T.Yonezawa

        Tissue and Cell Volume 58, June 2019, Pages 112-120

        CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling

        Tomoki Yoshioka, Tomoki Kosugi, Tomohiro Masuda, Tomoharu Watanabe, Akihiro Ryuge, Hiroshi Nagaya, Kayaho Maeda, YukaSato, Takayuki Katsuno, Noritoshi Kato, Takuji Ishimoto, Yukio Yuzawa, Shoichi Maruyama, Kenji Kadomatsu

        The American Journal of Pathology Volume 189, Issue 7, July 2019, Pages 1338-1350

        In vitro expansion of endogenous human alveolar epithelial type II cells in fibroblast-free spheroid culture

        Kazushige Shiraishi, Takuya Nakajima, Shigeyuki, Shichino, Shungo Deshimaru, Kouji Matsushima, Satoshi Ueha

        Biochemical and Biophysical Research Communications Volume 515, Issue 4, 6 August 2019, Pages 579-585

        Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis

        Keigo Nishida, Aiko Hasegawa, Satoru Yamasaki, Ryota Uchida, Wakana Ohashi, Yosuke Kurashima, Jun Kunisawa, Shunsuke

        Scientific Reports volume 9, Article number: 10842 (2019)

        Cationized liposomal keto-mycolic acids isolated from Mycobacterium bovis bacillus Calmette-Guérin induce antitumor immunity in a syngeneic murine bladder cancer model

        Takayuki Yoshino, Jun Miyazaki , Takahiro Kojima, Shuya Kandori, Masanobu Shiga, Takashi Kawahara, Tomokazu Kimura, Takashi Naka, Hideyasu Kiyohara, Miyuki Watanabe, Sho Yamasaki, Hideyuki Akaza, Ikuya Yano, Hiroyuki Nishiyama

        PLoS ONE 14(1): e0209196.

        Development of monoclonal mouse antibodies that specifically recognize pancreatic polypeptide

        Akemi Hara, Yuko Nakagawa, Keiko Nakao, Motoyuki Tamaki, Tetsuya Ikemoto, Mitsuo Shimada, Munehide Matsuhisa, Hiroki Mizukami, Nobuhiro Maruyama, Hirotaka Watada, Yoshio Fujitani

        Endocrine Journal

        Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

        Nobuhiro Tsuchiya, Rong Zhang, Tatsuaki Iwama, Norihiro Ueda, Tiany iLiu, Minako Tatsumi, Yutaka Sasaki, Ranmaru Shimoda, Yuki Osako, Yu Sawada, Yosuke Kubo, Azusa Miyashita, Satoshi Fukushima, Zhao Cheng, Ryo Nakaki, Keiyo Takubo, Seiji Okada, Shin Kaneko, Yasushi Uemura

        Cell Reports Volume 29, Issue 1, 1 October 2019, Pages 162-175.e9

        Establishment and characterization of patient‐derived organoids from a young patient with cervical clear cell carcinoma

        Yoshiaki Maru, Naotake Tanaka, Keiko Ebisawa, Akiko Odaka, Takahiro Sugiyama, Makiko Itami, and Yoshitaka Hippo

        Cancer Sci. 2019 Sep; 110(9): 2992–3005.

        PMab-219: A monoclonal antibody for the immunohistochemical analysis of horse podoplanin

        Yoshikazu Furusawa, Shinji Yamada, Shunsuke Itai, Takuro Nakamura, Miyuki Yanaka, Masato Sano, Hiroyuki Harada, Masato Fukui, Mika K.Kaneko, Yukinari Kato

      • Biochemistry and Biophysics ReportsVolume 18, July 2019, 100616

Development of an anti-bear podoplanin monoclonal antibody PMab-247 for immunohistochemical analysis

Yoshikazu Furusawa, Junko Takei, Yusuke Sayama, Shinji Yamada, Mika K.Kaneko, Yukinari Kato

Biochemistry and Biophysics Reports
Volume 18, July 2019, 100644

 

    • Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody DzMab-1 for Immunohistochemical Analyses

      Masato Sano, Mika K. Kaneko, and Yukinari Kato

      Monoclonal Antibodies in Immunodiagnosis and ImmunotherapyVol. 38, No. 4

      LGR5 expression predicts peritoneal recurrence after curative resection of primary colon cancer

      Hiroshi Nagata, Soichiro Ishihara, Hiroyuki Abe, Tetsuo Ushiku, Junko Kishikawa, Toshiaki Tanaka, Keisuke Hata, Kazushige Kawai, Masashi Fukayama & Hiroaki Nozawa

      British Journal of Cancer volume 120, pages996–1002(2019)

      Establishment of an Anticetacean Podoplanin Monoclonal Antibody PMab-237 for Immunohistochemical Analysis

      Yukinari Kato, Yoshikazu Furusawa, Shunsuke Itai, Junko Takei, Takuro Nakamura, Masato Sano, Hiroyuki Harada, Shinji Yamada, and Mika K. Kaneko

      Monoclonal Antibodies in Immunodiagnosis and ImmunotherapyVol. 38, No. 3

      ERO1α is a novel endogenous marker of hypoxia in human cancer cell lines

      Norio Takei, Akihiro Yoneda, Marina Kosaka, Kaori Sakai-Sawada & Yasuaki Tamura

      BMC Cancer volume 19, Article number: 510 (2019)

      Significant antitumor effect of an antibody against TMEM180, a new colorectal cancer‐specific molecule

      Masahiro Yasunaga, Shinji Saijou, Shingo Hanaoka, Takahiro Anzai, Ryo Tsumura, Yasuhiro Matsumura

      Cancer Sci. 2019 Feb; 110(2): 761-770.

      Efficient use of patient-derived organoids as a preclinical model for gynecologic tumors

      Yoshiaki Maru, Naotake Tanaka, Makiko Itami, Yoshitaka Hippo

      Gynecologic Oncology Volume 154, Issue 1, July 2019, Pages 189-198

      Constitutive activation of mTORC1 signaling induced by biallelic loss-of-function mutations in SZT2 underlies a discernible neurodevelopmental disease

      Yuji Nakamura, Kohji Kato, Naomi Tsuchida, Naomichi Matsumoto, Yoshiyuki Takahashi, Shinji Saitoh

      PLoS ONE 14(8): e0221482.

      Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis

      Yoshinori Takei, Shunsuke Takahashi, Masao Nakasatomi, Toru Sakairi, Hidekazu Ikeuchi, Yoriaki Kaneko, Keiju Hiromura, Yoshihisa Nojima, Akito Maeshima

      PLoS ONE 14(10): e0223703.

      Hormonal Regulation of Patient-Derived Endometrial Cancer Stem-like Cells Generated by Three-Dimensional Culture

      Sachiko Shiba, Kazuhiro Ikeda, Takashi Suzuki, Daisuke Shintani, Koji Okamoto, Kuniko Horie-Inoue, Kosei Hasegawa, Satoshi Inoue

      Endocrinology, Volume 160, Issue 8, August 2019, Pages 1895–1906

      Multicenter experience with large panel next-generation sequencing in patients with advanced solid cancers in Japan

      Shingo Kato, Takuo Hayashi, Yoshiyuki Suehara, Haruka Hamanoue, Shoji Yamanaka, Yasushi Ichikawa, Takuma Higurashi, Kenichi Ohashi, Shigeo Yamaguchi, Yumi Nozaki, Yasuhisa Terao, Tsuyoshi Saito

      Japanese Journal of Clinical Oncology, Volume 49, Issue 2, February 2019, Pages 174–182

      Characterization of spontaneous spheroids from oral mucosa-derived cells and their direct comparison with spheroids from skin-derived cells

      Ni Li, Xianqi Li, Kai Chen, Hongwei Dong & Hideaki Kagami

      Stem Cell Research & Therapy volume 10, Article number: 184 (2019)

      Natural Flavonol, Myricetin, Enhances the Function and Survival of Cryopreserved Hepatocytes In Vitro and In Vivo

      Changhao Cui 1, Shin Enosawa, Hitomi Matsunari, Hiroshi Nagashima and Akihiro Umezawa

      Int. J. Mol. Sci. 2019, 20(24), 6123

      Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells

      Hideharu Abe, Akiko Sakurai, Arisa Ochi

      Biochemical and Biophysical Research Communications Volume 508, Issue 2, 8 January 2019, Pages 654-659

      Localization of the ultraviolet-sensor Opn5m and its effect on myopia-related gene expression in the late-embryonic chick eye

      Mutsuko Kato, Keita Sato, Munenori Habuta, Hirofumi Fujita, Tetsuya Bando, Yuki Morizane, Fumio Shiraga, Satoru Miyaishi, Hideyo Ohuchi

      Biochemistry and Biophysics Reports Volume 19, September 2019, 100665

      Regulation of IGF-I by IGFBP3 and IGFBP5 during odontoblast differentiation in mice

      Chisato Aizawa, Kotaro Saito, Hayato Ohshima

      Journal of Oral Biosciences Volume 61, Issue 3, September 2019, Pages 157-162

      Histology and molecular biology studies on the expression and localization of angiopoietin‑like protein 8 in human tissues

      Naohiko Akimoto, Ryuichi Wada, Katsuhiko Iwakiri, Zenya Naito

      Biomedical Reports, November-2019 Volume 11 Issue 5

      Involvement of natriuretic peptide system in C2C12 myocytes

      Kiyoshi Ishikawa, Taiki Hara, Kana Kato, Takeshi Shimomura & Kenji Omori

      Molecular and Cellular Biochemistry volume 456, pages15–27(2019)

      ESTABLISHMENT AND CHARACTERIZATION OF PATIENT-DERIVED PLEOMORPHIC RHABDOMYOSARCOMA MODELS

      Rieko OYAMA, Mami TAKAHASHI, Fusako KITO, Marimu SAKUMOTO, Yoko TAKAI, Kumiko SHIOZAWA, Zhiwei QIAO, Shunichi TOKI, Yoshikazu TANZAWA, Akihiko YOSHIDA, Akira KAWAI, Tadashi KONDO

      Tiss. Cult. Res. Commun. 38: 1–12 (2019)

      Stat3 is indispensable for damage‐induced crypt regeneration but not for Wnt‐driven intestinal tumorigenesis

      Hiroko Oshima, Sau-Yee Kok, Mizuho Nakayama, Kazuhiro Murakami, Dominic Chih-Cheng Voon, Takashi Kimura, Masanobu Oshima

      FASEB, Volume33, Issue2 February 2019 Pages 1873-1886

      Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity

      Satoshi Endo, Toshiyuki Matsunaga, Akira Hara

      Archives of Biochemistry and Biophysics Volume 674, 15 October 2019, 108096

      Spontaneously Formed Spheroids from Mouse Compact Bone-Derived Cells Retain Highly Potent Stem Cells with Enhanced Differentiation Capability

      Kai Chen, Xianqi Li, Ni Li, Hongwei Dong, Yiming Zhang, Michiko Yoshizawa, and Hideaki Kagami

      Stem Cells International / 2019 / Article ID 8469012

      Immortalization of human zone I hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing

      Manami Nishiwaki, Masashi Toyoda, Yoshie Oishi, Seiichi Ishida, Shin-ichiro Horiuchi, Hatsune Makino, Tohru Kimura, Shin-ichi Ohno, Takashi Ohkura, Shin Enosawa, Hidenori Akutsu, Atsuko Nakazawa, Mureo Kasahara, Tohru Kiyono, Akihiro Umezawa

      bioRxiv, Posted August 08, 2019.

      The putative role of insulin-like growth factor (IGF)-binding protein 5 independent of IGF in the maintenance of pulpal homeostasis in mice

      Kotaro Saito,Hayato Ohshima

      Regenerative Therapy Volume 11, 1 December 2019, Pages 217-224

      The Integration of a Three-Dimensional Spheroid Cell Culture Operation in a Circulating Tumor Cell (CTC) Isolation and Purification Process: A Preliminary Study of the Clinical Significance and Prognostic Role of the CTCs Isolated from the Blood Samples of Head and Neck Cancer Patients

      Chia-Jung Liao, Chia-Hsun Hsieh, Feng-Chun Hung, Hung-Ming Wang, Wen-Pin Chou and Min-Hsien Wu

      Cancers 2019, 11(6), 783

      Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B

      Yoshito Nishimura, Hidenori Wake, Kiyoshi Teshigawara, Dengli Wang, Masakiyo Sakaguchi, Fumio Otsuka, Masahiro Nishibori

      Pharmacol Res Perspect. 2019;00:e00481.

      Spontaneously Formed Spheroids from Mouse Compact Bone-Derived Cells Retain Highly Potent Stem Cells with Enhanced Differentiation Capability

      Kai Chen, Xianqi Li, Ni Li, Hongwei Dong, Yiming Zhang, Michiko Yoshizawa and Hideaki Kagami

      Stem Cells International Volume 2019, Article ID 8469012, 13

      Theoretical modeling reveals that regulatory T cells increase T-cell interaction with antigen-presenting cells for stable immune tolerance

      Tomoyuki Yamaguchi, Shunsuke Teraguchi, Chikara Furusawa, Hiroaki Machiyama, Tomonobu M Watanabe, Hideaki Fujita, Shimon Sakaguchi, Toshio Yanagida

      International Immunology, Volume 31, Issue 11, November 2019, Pages 743–753

      Culture of hybrid spheroids composed of calcium phosphate materials and mesenchymal stem cells on an oxygen-permeable culture device to predict in vivo bone forming capability

      Tomoya Satoa, Takahisa Anada, Ryo Hamai, Yukari Shiwaku, Kaori Tsuchiya, Susumu Sakai, Kazuyoshi Baba, Keiichi Sasaki, Osamu Suzuki

      Acta Biomaterialia Volume 88, 1 April 2019, Pages 477-490

      Progesterone receptor isoform B expression in pulmonary neuroendocrine cells decreases cell proliferation

      Teeranut Asavasupreechar, Ryoko Saito, Dean P.Edwards, Hironobu Sasano, Viroj Boonyaratanakornkit

      The Journal of Steroid Biochemistry and Molecular Biology Volume 190, June 2019, Pages 212-223

      Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice

      Takako Saito, Ikuo Wada & Naokazu Inoue

      Scientific Reports volume 9, Article number: 3151 (2019)

      Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis

      Koji Hirata, Sota Kodama, Yasuhiro Nakano, Yasuko Minaki-Nakagawa, Yoshiki Aoyama, Morito Sakikubo, Toshihiko Goto, Masahiro Yoshida, Toshihiko Masui, Takuya Yamamoto, Shinji Uemoto & Yoshiya Kawaguchi

      Scientific Reports volume 9, Article number: 1636 (2019)

      Newly developed anti‐S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis

      Rie Kinoshita, Hiroki Sato, Akira Yamauchi, Yuta Takahashi, Yusuke Inoue, I Wayan Sumardika, Youyi Chen, Nahoko Tomonobu, Kota Araki, Kazuhiko Shien, Shuta Tomida, Hidejiro Torigoe, Kei Namba,Eisuke Kurihara, Yusuke Ogoshi, Hitoshi Murata, Ken‐ichi Yamamoto, Junichiro Futami, Endy Widya Putranto, I Made Winarsa Ruma, Hiromasa Yamamoto, Junichi Soh, Toshihiko Hibino, Masahiro Nishibori, Eisaku Kondo, Shinichi Toyooka, Masakiyo Sakaguchi

      Int. J. Cancer: 145, 569–575 (2019)

      Selective role of neurokinin B in IL-31–induced itch response in mice

      Daiji Sakata, Takehito Uruno, Keisuke Matsubara, Tsugunobu Andoh, Kazuhiko Yamamura, Yuki Magoshi,Kazufumi Kunimura, Yasuhisa Kamikaseda, Masutaka Furue, Yoshinori Fukui

      Journal of Allergy and Clinical Immunology, VOLUME 144, ISSUE 4, P1130-1133.E8, OCTOBER 01, 2019

      FGF10/FGFR2/ERK Signal Activation is Required for the Initiation, Maintenance and Progression of Intraductal Papillary Neoplasm of the Bile Duct

      Hiroyuki Tomita, Kaori Tanaka, Akihiro Hirata,Hideshi Okada, Hisashi Imai, Yohei Shirakami, Kotaro Ohnishi, Shigeyuki Sugie, Hitomi Aoki, Yuichiro Hatano, Kei Noguchi, Tomohiro Kanayama, Ayumi Niwa, Natsuko Suzui, Tatsuhiko Miyazaki, Takuji Tanaka, Haruhiko Akiyama, Masahito Shimizu, Kazuhiro Yoshida, Akira Hara

      Cell Reports, 61 Pages Posted: 8 Nov 2019

      A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells

      Shogo Ohta, Tetsuya Ikemoto, Yuma Wada, Yu Saito, Shinichiro Yamada, Satoru Imura, Yuji Morine & Mitsuo Shimada

      Scientific Reports volume 9, Article number: 18731 (2019)

      Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells

      Takashi Kijima, Hiroshi Nakagawa, Masataka Shimonosono, Prasanna M.Chandramouleeswaran, Takeo Hara, Varun Sahu, Yuta Kasagi, Osamu Kikuchi, Koji Tanaka, Veronique Giroux, Amanda B.Muir, Kelly A.Whelan, Shinya Ohashi, Seiji Naganuma, Andres J.Klein-Szanto, Yoshiaki Shinden, Ken Sasaki, Itaru Omoto, Yoshiaki Kita, Manabu Muto, Adam J.Bass, J. Alan Diehl, Gregory G.Ginsberg, Yuichiro Doki, Masaki Mori, Yasuto Uchikado, Takaaki Arigami, Narayan G.Avadhani, Devraj Basu, Anil K.Rustgi, Shoji Natsugoe

      Cellular and Molecular Gastroenterology and Hepatology Volume 7, Issue 1, 2019, Pages 73-91

      ESR1-Stabilizing Long Noncoding RNA TMPO-AS1 Promotes Hormone-Refractory Breast Cancer Progression

      Yuichi Mitobe, Kazuhiro Ikeda, Takashi Suzuki, Kiyoshi Takagi, Hidetaka Kawabata, Kuniko Horie-Inoue, Satoshi Inoue

      Molecular and Cellular Biology, 2019, e00261-19

      CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome

      Motoko Unoki, Hironori Funabiki, Guillaume Velasco, Claire Francastel and Hiroyuki Sasaki

      J Clin Invest. 2019;129(1):78-92

      Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine

      Makiko Kawaguchi, Koji Yamamoto, Naoki Takeda, Tsuyoshi Fukushima, Fumiki Yamashita, Katsuaki Sato, Kenichiro Kitamura, Yoshitaka Hippo, James W. Janetka & Hiroaki Kataoka

      Communications Biology volume 2, Article number: 11 (2019)

      TRAF6 maintains mammary stem cells and promotes pregnancy-induced mammary epithelial cell expansion

      Mizuki Yamamoto, Chiho Abe, Sakura Wakinaga, Kota Sakane, Yo Yumiketa, Yuu Taguchi, Takayuki Matsumura, Kosuke Ishikawa, Jiro Fujimoto, Kentaro Semba, Maki Miyauchi, Taishin Akiyama & Jun-ichiro Inoue

      Communications Biology volume 2, Article number: 292 (2019)

      Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection

      Miki Arai Hojo, Kyoko Masuda, Hiroaki Hojo, Yosuke Nagahata, Keiko Yasuda, Daiya Ohara, Yusuke Takeuchi, Keiji Hirota, Yutaka Suzuki, Hiroshi Kawamoto & Shinpei Kawaoka

      Nature Communications volume 10, Article number: 2603 (2019)

      Loss of the adhesion G-protein coupled receptor ADGRF5 in mice induces airway inflammation and the expression of CCL2 in lung endothelial cells

      Fumimasa Kubo, Donna Maretta Ariestanti, Souta Oki, Taku Fukuzawa, Ryotaro Demizu, Tomoya Sato, Rahmaningsih Mara Sabirin, Shigehisa Hirose & Nobuhiro Nakamura

      Respiratory Research volume 20, Article number: 11 (2019)

      Identification, characterization, and structural analyses of a fungal endo-β-1,2-glucanase reveal a new glycoside hydrolase family

      Nobukiyo Tanaka, Masahiro Nakajima, Megumi Narukawa-Nara, Hiroki Matsunaga, Shinji Kamisuki, Hiroki Aramasa, Yuta Takahashi, Naohisa Sugimoto, Koichi Abe, Tohru Terada, Akimasa Miyanaga, Tetsuro Yamashita, Fumio Sugawara, Takashi Kamakura, Shiro Komba, Hiroyuki Nakai and Hayao Taguchi

      J. Biol. Chem. (2019) 294(19) 7942–7965

      Stromal fibroblasts induce metastatic tumor cell clusters via epithelial–mesenchymal plasticity

      Yuko Matsumura, Yasuhiko Ito, Yoshihiro Mezawa, Kaidiliayi Sulidan, Yataro Daigo, View ORCID ProfileToru Hiraga, Kaoru Mogushi, Nadila Wali, Hiromu Suzuki, View ORCID ProfileTakumi Itoh, Yohei Miyagi, View ORCID ProfileTomoyuki Yokose, Satoru Shimizu, Atsushi Takano, Yasuhisa Terao, Harumi Saeki, Masayuki Ozawa, Masaaki Abe, Satoru Takeda, Ko Okumura, Sonoko Habu, Okio Hino, View ORCID ProfileKazuyoshi Takeda, View ORCID ProfileMichiaki Hamada, View ORCID ProfileAkira Orimo

      Life Science Alliance, Volume 2, No. 4 August 2019

      【2018】

      Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation

      Sakurako Goto-Ito, Atsushi Yamagata, Yusuke Sato, Takeshi Uemura, Tomoko Shiroshima, Asami Maeda, Ayako Imai, Hisashi Mori, Tomoyuki Yoshida & Shuya Fukai
      Nature Communicationsvolume , Article number: 269 (2018)

      Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

      Seitaro Nomura, Masahiro Satoh, Takanori Fujita, Tomoaki Higo, Tomokazu Sumida, Toshiyuki Ko, Toshihiro Yamaguchi, Takashige Tobita, Atsuhiko T. Naito, Masamichi Ito, Kanna Fujita, Mutsuo Harada, Haruhiro Toko, Yoshio Kobayashi, Kaoru Ito, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Hiroyuki Aburatani & Issei Komuro

      Nature Communicationsvolume,4435 (2018)

      HtrA1 Is Specifically Up-Regulated in Active Keloid Lesions and Stimulates Keloid Development

      Satoko Yamawaki, Motoko Naitoh,* Hiroshi Kubota, Rino Aya, Yasuhiro Katayama, Toshihiro Ishiko, Taku Tamura, Katsuhiro Yoshikawa, Tatsuki Enoshiri, Mika Ikeda, and Shigehiko Suzuki

      Int J Mol Sci.2018 May; 19(5): 1275.

      Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension

      Fumiko Kawakami-Mori,1,2 Mitsuhiro Nishimoto,1 Latapati Reheman,3 Wakako Kawarazaki,1 Nobuhiro Ayuzawa,1 Kohei Ueda,1 Daigoro Hirohama,1 Daisuke Kohno,4 Shigeyoshi Oba,1 Tatsuo Shimosawa,3 Takeshi Marumo,1 and Toshiro Fujitacorresponding author

      JCI Insight.JCI Insight.

      Protein kinase C-δ signaling regulates glucagon secretion from pancreatic islets

      Kiyotake Yamamoto, Hiroyuki Mizuguchi, Natsumi Tokashiki, Makoto Kobayashi, Motoyuki Tamaki, Youichi Sato, Hiroyuki Fukui, Aiko Yamauchi

      The Journal of Medical Investigation,2017 年 64 巻 1.2 号 p. 122-128

      Prognostic significance of PIK3CA mutation in stage IIB to IVA cervical cancers treated by concurrent chemoradiotherapy with weekly cisplatin

      Bouchra Lachkar, ,Takeo Minaguchi, Azusa Akiyama, Shuling Liu,b Shuang Zhang, Chenyang Xu, Ayumi Shikama, Nobutaka Tasaka, Manabu Sakurai,  Sari Nakao, Hiroyuki Ochi, Hiroyuki Yoshikawa, Toyomi Satoh

      Medicine (Baltimore),2018 Aug; 97(31)

      Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice

      Shin-Ichi Inoue Shingo Takahara Takeo Yoshikawa Tetsuya Niihori Kazuhiko Yanai Yoichi Matsubara Yoko Aoki

      Human Molecular Genetics , Volume 26, Issue 23, 1 December 2017, Pages 4715–4727

      Biomimetic Chemical Sensing by Fluorescence Signals Using a Virus-like Particle-Based Platform

      Yuki Kushida , Yoshiyuki Arai , Ken Shimono, and Takeharu Nagai

      ACS Sens. 2018, 3, 87−92

      Contribution of Thyrotropin-Releasing Hormone to Cerebellar Long-Term Depression and Motor Learning

      Masashi Watanave, Yasunori Matsuzaki, Yasuyo Nakajima, Atsushi Ozawa, Masanobu Yamada and Hirokazu Hirai

      Front. Cell. Neurosci.  12-Dec-2018

      Induction of steady-state glomeruloid sphere by self-assembly from human embryonic kidney cells

      HideharuAbeAkikoSakuraiArisaOchi

      Biochemical and Biophysical Research Communications , Volume 508, Issue 2, 8 January 2019, Pages 654-659

      Plasma Irradiation Effects to Intra- Abdominal Organs Compared with Adhesion Mouse Model

      Keita Soda,a, Hiroharu Yamashita, Kyungho Chang, Takeshi Kawamura, Takao Hamakuboa & Nobuyuki Shimizu

      Plasma Medicine , 7(4):347–381 (2017)

      ESTABLISHMENT AND CHARACTERIZATION OF A PATIENT-DERIVED CANCER MODEL OF UNDIFFERENTIATED PLEOMORPHIC SARCOMA

      Fusako KITO, Rieko OYAMA, Mami TAKAHASHI, Kumiko SHIOZAWA, Marimu SAKUMOTO, Akihiko YOSHIDA, Noritaka SETSU, Eisuke KOBAYASHI, Akira KAWAI, Tadashi KONDO

      組織培養研究 , 2018 年 37 巻 2 号 p. 133-145

      Effects of controlled abnormal joint movement on the molecular biological response in intra-articular tissues during the acute phase of anterior cruciate ligament injury in a rat model

      Yuichi Nishikawa, Takanori Kokubun, Naohiko Kanemura, Tetsuya Takahashi, Masayasu Matsumoto, Hirofumi Maruyama and Kiyomi Takayanagi

      BMC Musculoskeletal Disorders , 201819:175

      Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues

      Hirosumi Tamura Arisa Higa Hirotaka Hoshi Gen Hiyama Nobuhiko Takahashi Masae Ryufuku Gaku Morisawa Yuka Yanagisawa Emi Ito Jun-Ichi Imai Yuu Dobashi Kiyoaki Katahira Shu Soeda Takafumi Watanabe Keiya Fujimori Shinya Watanabe Motoki Takagi

      Oncology Reports , 8月 2018,Volume 40 Issue 2

      Psychological stress in aged female mice causes acute hypophagia independent of central serotonin 2C receptor activation

      Chinami Matsumoto, Chihiro Yamada, Chiharu Sadakane, Miwa Nahata, Tomohisa Hattori , Hiroshi Takeda

      PLOS ONE , 10-Nov-2017

      【2017】

      Disturbed chromosome segregation and multipolar spindle formation in a patient with CHAMP1 mutation

      Nobuhiko Okamoto Yuki Tsuchiya Ichiro Kuki Toshiyuki Yamamoto Hirotomo Saitsu Daiju Kitagawa Naomichi Matsumoto
      Molecular Genetics & Genomic Medicine,Volume5, Issue5,September 2017,Pages 585-591

      Expression of CGRP, Vasculogenesis and Osteogenesis Associated mRNAs in the Developing Mouse Mandible and Tibia

      Yuuki Maeda, Yoko Miwa, and  Iwao Sato
      Eur J Histochem, 2017 Jan 23; 61(1): 2750.

      Identification of Stem Cells in the Epithelium of the Stomach Corpus and Antrum of Mice

      Junichi Matsuo, Shunichi Kimura, Akihiro Yamamura, Cai Ping Koh, Md Zakir Hossain, Dede Liana Heng, Kazuyoshi Kohu, Dominic Chih-Cheng Voon, Hiroshi Hiai, Michiaki Unno
      Gastroenterology,Volume 152, Issue 1, January 2017, Pages 218–231.e14

      Simvastatin Up-Regulates Annexin A10 That Can Inhibit the Proliferation, Migration, and Invasion in Androgen-Independent Human Prostate Cancer Cells

      Yoshiyuki Miyazawa,Yoshitaka Sekine, Haruo Kato, Yosuke Furuya, Hidekazu Koike,and Kazuhiro Suzuki
      The Prostate,Volume 77, Issue 4March 1, 2017 Pages 337–349

      Purinergic dysregulation causes hypertensive glaucoma–like optic neuropathy

      Youichi Shinozaki,Kenji Kashiwagi,Kazuhiko Namekata,Akiko Takeda,Nobuhiko Ohno,Bernard Robaye,Takayuki Harada,Takeshi Iwata,and Schuichi Koizumi
      JCI Insight. 2017 Oct 5; 2(19)

      Syntaxin 4a Regulates Matrix Vesicle-Mediated Bone Matrix Production by Osteoblasts

      Shinji Kawai,Ikumi Michikami,Jirouta Kitagaki,Kenji Hata,Hiroshi Kiyonari,Takaya Abe,Atsuo Amano,Satoshi Wakisaka
      JBMR,Volume 32, Issue 3 March 2017 Pages 440–448

      In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs)

      Nobumichi Ohoka, Keiichiro Okuhira, Masahiro Ito, Katsunori Nagai, Norihito Shibata, Takayuki Hattori, Osamu Ujikawa, Kenichiro Shimokawa, Osamu Sano, Ryokichi Koyama, Hisashi Fujita, Mika Teratani, Hirokazu Matsumoto, Yasuhiro Imaeda
      JBC,VOL. 292, NO. 11, pp. 4556–4570, March 17, 2017

      ESTABLISHMENT AND CHARACTERIZATION OF CELL LINE OF UNDIFFERENTIATED PLEOMORPHIC SARCOMA

      Fusako KITO, Rieko OYAMA, Mami TAKAHASHI, Kumiko SHIOZAWA, Marimu SAKUMOTO, Akihiko YOSHIDA, Noritaka SETSU, Eisuke KOBAYASHI, Akira KAWAI, Tadashi KONDO
      組織培養研究 2017 年 36 巻 5 号 p. 41-48

      Establishment and proteomic characterization of NCC-LMS1-C1, a novel cell line of primary leiomyosarcoma of the bone

      Marimu Sakumoto Mami Takahashi Rieko Oyama Yoko Takai Fusako Kito Kumiko Shiozawa Zhiwei Qiao Akihiko Yoshida Makoto Endo Akira Kawai Tadashi Kondo

      Japanese Journal of Clinical Oncology , Volume 47, Issue 10, 1 October 2017, Pages 954–961

      cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren’s syndrome

      H. Takahashi H. Tsuboi H. Asashima T. Hirota Y. Kondo M. Moriyama I. Matsumoto S. Nakamura T. Sumida

      Clinical and Experimental Immunology , Volume190, Issue1,October 2017,Pages 96-109

      変形性関節症および関節リウマチ患者由来ヒト滑膜細胞の軟骨分化能

      大西-笠松 礼, 小阪 拓男, 佐藤 元信, 山田-内尾 こずえ, 吉田 東歩, 小原 有弘

      組織培養研究 , 2017 年 36 巻 1 号 p. 1-11

      【2016】

      Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

      Satoko Arai,Kento Kitada,Tomoko Yamazaki,Ryosuke Takai,Xizhong Zhang,Yoji Tsugawa,Ryoichi Sugisawa,Ayaka Matsumoto,Mayumi Mori,Yasunori Yoshihara,Kent Doi,Natsumi Maehara,Shunsuke Kusunoki,Akiko Takahata,Eisei Noiri,Yusuke Suzuki,Naoki Yahagi,Akira Nishiyama,Lakshman Gunaratnam,Tomoko Takano& Toru Miyazaki
      Nature Medicine,2, 183–193 (2016)

      Expression and Function of Group IIE Phospholipase A2 in Mouse Skin

      Kei Yamamoto, Yoshimi Miki, Hiroyasu Sato, Yasumasa Nishito, Michael H. Gelb, Yoshitaka Taketomi and Makoto Murakami
      JBC,VOL. 291, NO. 30, pp. 15602–15613, July 22, 2016

      TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal

      Michitaka Oho, Risa Nakano, Ryutarou Nakayama, Wataru Sakurai, Azusa Miyamoto, Yoshikazu Masuhiro and Shigemasa Hanazawa
      JBC,VOL. 291, NO. 43, pp. 22650–22660, October 21, 2016

      ASBEL–TCF3 complex is required for the tumorigenicity of colorectal cancer cells

      Kenzui Taniuea, Akiko Kurimotoa,, Yasuko Takeda, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yuki Katou, Katsuhiko Shirahige, and Tetsu Akiyama
      PNAS,vol. 113 no. 45 Kenzui Taniue, 12739–12744

      Human adipocytes from the subcutaneous superficial layer have greater adipogenic potential and lower PPAR-γ DNA methylation levels than deep layer adipocytes

      Kentaro Kosaka, Yoshitaka Kubota, Naoki Adachi, Shinsuke Akita, Yoshitaro Sasahara, Tomoe Kira, Masayuki Kuroda, Nobuyuki Mitsukawa, Hideaki Bujo, Kaneshige Satoh
      Cell Physiology,2016 Vol. 311 no. 2,

      Expression of CGRP in embryonic mouse masseter muscle

      Yuri Azuma, Yoko Miwa, Iwao Sato
      Annals of Anatomy – Anatomischer Anzeiger,Volume 206, July 2016, Pages 34–47

      Fgf20 and Fgf4 may contribute to tooth agenesis in epilepsy-like disorder mice

      Nao Ogawa, Kunihiko Shimizu
      Pediatric Dental Journal,Volume 26, Issue 1, April 2016, Pages 21–27

      TissuVolume 26, Issue 1, April 2016, Pages 21–27e distribution of aryl hydrocarbon receptor in the intestine: Implication of putative roles in tumor suppression

      Togo Ikuta , Masafumi Kurosumi, Toshimasa Yatsuoka, Yoji Nishimura
      Experimental Cell Research,Volume 343, Issue 2, 1 May 2016, Pages 126–134

      Histological and radiographic study of human edentulous and dentulous maxilla

      Yukino KamigakiIwao SatoTakashi Yosue
      Anatomical Science International, 11 April 2016, pp 1–13

      Novel round cells in urine sediment and their clinical implications

      Kenichi Shukuya, b, Sayoko Ogura, Yasunori Tokuhara, Shigeo Okubo, Yutaka Yatomi, Minoru Tozuka, Tatsuo Shimosawa
      Clinica Chimica Acta, Volume 457, 1 June 2016, Pages 142–149

      Sphere-formation culture of testicular germ cells in the common marmoset, a small New World monkey

      Zachary Yu-Ching Lin, OrieHikabe, Sadafumi Suzuki, Takamasa Hirano, Haruhiko Siomi, Erika Sasaki, Masanori Imamura, Hideyuki Okano
      Primates, January 2016, Volume 57, Issue 1, pp 129–135

      Imaging Flow Cytometry Analysis to Identify Differences of Survival Motor Neuron Protein Expression in Patients With Spinal Muscular Atrophy

      Reiko Arakawa, Masayuki Arakawa, Kaori Kaneko,Noriko Otsuki, Ryoko Aoki, Kayoko Saito
      Pediatric Neurology, Volume 61, August 2016, Pages 70–75

      Direct visualization of replication dynamics in early zebrafish embryos

      Kenji Kuriya, Eriko Higashiyama, Eriko Avşar-Ban, Nanami Okochi, Kaede Hattori, Shin Ogata, Shin-ichiro Takebayashi, Masato Ogata, Yutaka Tamaru& Katsuzumi Okumura
      Bioscience, Biotechnology, and Biochemistry , Volume 80, 2016 – Issue 5

      The effect of hepatocyte growth factor on secretory functions in human eosinophils

      Yumiko Yamauchia, Shigeharu Uekia, Yasunori Konnoa, Wataru Ito, Masahide Takeda, Yuka Nakamura, Junko Nishikawa, Yuki Moritoki, Ayumi Omokawa, Tomoo Saga, Makoto Hirokawa
      Cytokine, Volume 88, December 2016, Pages 45–50

      Activation of 5-HT4 receptors facilitates neurogenesis from transplanted neural stem cells in the anastomotic ileum

      Kei Goto, Isao Kawahara, Hiroyuki Inada, Hiromi Misawa, Hiroki Kuniyasu, Junich Nabekura, Miyako Takaki
      The Journal of Physiological Sciences, January 2016, Volume 66, Issue 1, pp 67–76

      Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field

      Yuichiro Nishiyama, Akio Iwanami, Jun Kohyamab, Go Itakurab, Soya Kawabataa, Keiko Sugaia, Soraya Nishimuraa, Rei Kashiwagia, Kaori Yasutakea, Miho Isodab, c, Morio Matsumoto
      Neuroscience Research, Volume 107, June 2016, Pages 20–29

      Claudin-21 Has a Paracellular Channel Role at Tight Junctions

      Hiroo Tanaka, Yasuko Yamamoto, Hiroka Kashihara, Yuji Yamazaki, Kazutoshi Tani, Yoshinori Fujiyoshi, Katsuhiko Mineta, Kosei Takeuchi, Atsushi Tamura
      Mol. Cell. Biol, March 2016 vol. 36 no. 6 954-964

      Organoids as an ex vivo model for studying the serotonin system in the murine small intestine and colon epithelium

      Takeshi Tsuruta, Shinichi Saito, Yosuke Osaki, Akihiro Hamada, Ayako-Aoki Yoshida, Kei Sonoyama
      Biochemical and Biophysical Research Communications, Volume 474, Issue 1, 20 May 2016, Pages 161–167

      Isolation of adult pituitary stem/progenitor cell clusters located in the parenchyma of the rat anterior lobe

      Saishu Yoshida, Naoto Nishimura, Hiroki Ueharu, Naoko Kanno, Masashi Higuchi, Kotaro Horiguchi, Takako Kato, Yukio Kato
      Stem Cell Research, Volume 17, Issue 2, September 2016, Pages 318–329

      Thymic stromal lymphopoietin in tonsillar follicular dendritic cells correlates with elevated serum immunoglobulin A titer by promoting tonsillar immunoglobulin A class switching in immunoglobulin A nephropathy

      Hongxue Meng , Huining Li, Rintaro Ohe, Ye Aung Naing, Suran Yang, Takanobu Kabasawa, Tomoya Kato, Mitsumasa Osakabe, Hiroya Ohtake, Akihiro Ishida, Junli Lua, Lei Zhang

      Translational Research, Volume 176, October 2016, Pages 1–17

      Neonatal exposure to SERMs disrupts neuroendocrine development and postnatal reproductive function through alteration of hypothalamic kisspeptin neurons in female rats

      Ryohei Ichimura, Miwa Takahashi, Tomomi Morikawa, Kaoru Inoue, Kazunori Kuwata, Kento Usuda, Makoto Yokosuka, Gen Watanabe, Midori Yoshida
      NeuroToxicology, Volume 56, September 2016, Pages 64–75

      【2015】

      Glypican-5 Increases Susceptibility to Nephrotic Damage in Diabetic Kidney

      Koji Okamoto, Kenjiro Honda, Kent Doi, Tomoko Ishizu, Daisuke Katagiri, Takehiko Wada, Kenji Tomita, Takayasu Ohtake, Toyoji Kaneko, Shuzo Kobayashi, Masaomi Nangaku, Katsushi Tokunaga, and Eisei Noiri
      The American Journal of Pathology, Vol. 185, No. 7, July 2015

      Expression of DMP1 in the developing mouse tongue embryo

      Hidetaka Murata, Msataka Sunohara, Iwao Sato
      Annals of Anatomy 200 (2015) 136-148

      Ras Guanine Nucleotide-Releasing Protein 4 Is Aberrantly Expressed in the Fibroblast-like Synoviocytes of Patients With Rheumatoid Arthritis and Controls Their Proliferation

      Michihito Kono, Shinsuke Yasuda, Richard L. Stevens, Hideyuki Koide, Takashi Kurita, Yuka Shimizu, Yusaku Kanetsuka, Kenji Oku, Toshiyuki Bohgaki, Olga Amengual, Tetsuya Horita, Tomohiro Shimizu, Tokifumi Majima, Takao Koike, and Tatsuya Atsumi
      ARTHRITIS & RHEUMATOLOGY Vol. 67, No. 2, February 2015, pp 396-407

      The structure and conformational switching of Rap1B

      Hiroki Noguchi, Takahisa Ikegami, Aritaka Nagadoi, Yuji O. Kamatari, Sam-Yong Park, Jeremy R.H. Tame, Satoru Unzai
      Biochemical and Biophysical Research Communications 462 (2015) 46-51

      S-nitrosylation of mouse galectin-2 prevents oxidative inactivation by hydrogen peroxide

      Mayumi Tamura, Masanori Saito, Kaori Yamamoto, Tomoharu Takeuchi, Kazuo Ohtake, Hiroaki Tateno, Jun Hirabayashi, Jun Kobayashi, Yoichiro Arata
      Biochemical and Biophysical Research Communications 457 (2015) 712-717

      Splenic Gene Delivery System Using Self-assembling Nano-complex with Phosphatidylserine Analog

      Tomoaki Kurosaki, Chihiro Nakasone, Yukinobu Kodama, Kanoko Egashira, Hitomi Harasawa, Takahiro Muro, Hiroo Nakagawa, Takashi Kitahara, Norihide Higuchi, Tadahiro Nakamura, and Hitoshi Sasaki
      Biol. Pharm. Bull. 38, 23-29 (2015)

      The Critical Hormone-Sensitive Window for the Development of Delayed Effects Extends to 10 Days after Birth in Female Rats Postnatally Exposed to 17alpha-Ethynylestradiol

      Ryohei Ichimura, Miwa Takahashi, Tomomi Morikawa, Kaoru Inoue, Kazunori Kuwata, Kento Usuda, Makoto Yokosuka, Gen Watanabe, and Midori Yoshida
      BIOLOGY OF REPRODUCTION (2015) 93(2):32, 1?11

      High-throughput screening with nanoimprinting 3D culture for efficient drug development by mimicking the tumor environment [iPGell]

      Yukie Yoshii, Takako Furukawa, Atsuo Waki, Hiroaki Okuyama, Masahiro Inoue, Manabu Itoh, Ming-Rong Zhang, Hidekatsu Wakizaka, Chizuru Sogawa, Yasushi Kiyono, Hiroshi Yoshii, Yasuhisa Fujibayashi, Tsuneo Saga
      Biomaterials 51 (2015) 278-289

      Poly-3-hydroxybutyrate (PHB) production from alkylphenols, mono and poly-aromatic hydrocarbons using Bacillus sp. CYR1: A new strategy for wealth from waste [iPGell]

      M. Venkateswar Reddy, Yasuteru Mawatari, Yuka Yajima, Chigusa Seki, Tamotsu Hoshino, Young-Cheol Chang
      Bioresource Technology 192 (2015) 711-717

      MicroRNAs in retina during development of experimental autoimmune uveoretinitis in rats

      Takayo Watanabe, Hiroshi Keino, Akihiko Kudo, Yasuhiko Sato, Annabelle A Okada
      Br J Ophthalmol 2015;0:1-7

      Transient Ca2+ depletion from the endoplasmic reticulum is critical for skeletal myoblast differentiation

      Keiko Nakanishi, Kisa Kakiguchi, Shigenobu Yonemura, Akihiko Nakano, and Nobuhiro Morishima
      The FASEB Journal, Vol. 29 May 2015

      Inhibition of b-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo

      Yoshihiko Uehara, Masahiro Inoue, Koji Fukuda, Hiroyuki Yamakoshi, Yoshio Hosoi, Hiroaki Kanda, Masanobu Oshima, Yoshiharu Iwabuchi, Hiroyuki Shibata
      Gastric Cancer (2015) 18:774-783

      Degradation and conversion of toxic compounds into useful bioplastics by Cupriavidus sp. CY-1: relative expression of the PhaC gene under phenol and nitrogen stress [iPGell]

      M. Venkateswar Reddy, Yuka Yajima, Yasuteru Mawatari, Tamotsu Hoshinod, and Young-Cheol Chang
      Green Chem., 2015, 17, 4560

      Expression of myostatin in early postnatal mouse masseter and rectus femoris muscles

      Hiroshi Takada, Yoko Miwa and Iwao Sato
      Histol Histopathol (2015) 30: 1353-1365

      Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis

      Chihiro Ebihara, Ken Ebihara, Megumi Aizawa-Abe, Tomoji Mashimo, Tsutomu Tomita, Mingming Zhao, Valentino Gumbilai, Toru Kusakabe, Yuji Yamamoto, Daisuke Aotani, Sachiko Yamamoto-Kataoka, Takeru Sakai, Kiminori Hosoda, Tadao Serikawa and Kazuwa Nakao
      Human Molecular Genetics, 2015, Vol. 24, No. 15 4238-4249

      Orexin-A Inhibits the High Potassium-Induced Increase in Intracellular Calcium Levels in Cultured Dorsal Root Ganglions Neurons from Carrageenan-Treated Rats

      Masataka Kimura, Manabu Ishikawa, Asako Suzuki, Akio Uda, Masakazu Okubo, Morio Iijima, Noboru Kuboyama, and Yasuhiko Kawai
      Int J Oral-Med Sci 13(3):94-101, 2015

      AMP-activated Protein Kinase Suppresses Biosynthesis of Glucosylceramide by Reducing Intracellular Sugar Nucleotides

      Yohei Ishibashi and Yoshio Hirabayashi
      THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 29, pp. 18245-18260, July 17, 2015

      Factor B Is the Second Lipopolysaccharide-binding Protease Zymogen in the Horseshoe Crab Coagulation Cascade

      Yuki Kobayashi, Toshiaki Takahashi, Toshio Shibata, Shunsuke Ikeda, Takumi Koshiba, Hikaru Mizumura, Toshio Oda, and Shun-ichiro Kawabata
      THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 31, pp. 19379-19386, July 31, 2015

      Degradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary Disorders

      Norihito Shibata, Nobumichi Ohoka, Yusuke Sugaki, Chiaki Onodera, Mizuho Inoue, Yoshiyuki Sakuraba, Daisuke Takakura, Noritaka Hashii, Nana Kawasaki, Yoichi Gondo, and Mikihiko Naito
      THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 290, NO. 47, pp. 28428-28437, November 20, 2015

      Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs: tumor model to assay of tumor response to photodynamic therapy

      Norihiro Honda, Yoichiro Kariyama, Hisanao Hazama, Takuya Ishii, Yuya Kitajima, Katsushi Inoue, Masahiro Ishizuka, Tohru Tanaka, and Kunio Awazu
      Journal of Biomedical Optics 20(12), 125001 (December 2015)

      Gonadotropin regulation and role of ovarian osteopontin in the periovulatory period

      Yoshimitsu Kuwabara, Akira Katayama, Ryoko Tomiyama, Hu Piao, Sachiko Kurihara, Shuichi Ono, Katsuya Mine, Shigeo Akira, Hideo Orimo and Toshiyuki Takeshita
      Journal of Endocrinology (2015) 224, 49-59

      The role of group IIF-secreted phospholipase A2 in epidermal homeostasis and hyperplasia

      Kei Yamamoto, Yoshimi Miki, Mariko Sato, Yoshitaka Taketomi, Yasumasa Nishito, Choji Taya, Kazuaki Muramatsu, Kazutaka Ikeda, Hiroki Nakanishi, Ryo Taguchi, Naotomo Kambe, Kenji Kabashima, Gerard Lambeau, Michael H. Gelb, and Makoto Murakami
      J. Exp. Med. 2015 Vol. 212 No. 11 1901-1919

      Expression profiles of human CCN genes in patients with osteoarthritis or rheumatoid arthritis

      Masatoshi Komatsu, Yukio Nakamura, Masaaki Maruyama, Kazutoshi Abe, Ramida Watanapokasin, Hiroyuki Kato
      J Orthop Sci (2015) 20:708-716

      A protein tyrosine kinase receptor, c-RET signaling pathway contributes to the enteric neurogenesis induced by a 5-HT4 receptor agonist at an anastomosis after transection of the gut in rodents

      Kei Goto, Isao Kawahara, Hiroki Kuniyasu, Miyako Takaki
      J Physiol Sci (2015) 65:377-383

      Congenital malformation of the vaginal orifice, imperforate vagina, in the common marmoset (Callithrix jacchus)

      Kimie NIIMI, Ayaka OGUCHI, Kenji NISHIO, Yasushi OKANO and Eiki TAKAHASHI
      J. Vet. Med. Sci. 77(3): 345-348, 2015

      Establishment of a panel of in-house polyclonal antibodies for the diagnosis of enterovirus infections [iPGell]

      Osamu Kotani, Naoko Iwata-Yoshikawa, Tadaki Suzuki, Yuko Sato, Noriko Nakajima, Satoshi Koike, Takuya Iwasaki, Tetsutaro Sata, Teruo Yamashita, Hiroko Minagawa, Fumihiro Taguchi, Hideki Hasegawa, Hiroyuki Shimizu and Noriyo Nagata
      Neuropathology 2015; 35, 107-121

      A New System to Evaluate the Influence of Immunosuppressive Drugs on Pancreatic Islets Using Epigenetic Analysis in a 3-Dimensional Culture [iPGell]

      Masaki Nagaya, Yoshikazu Arai, Hitomi Matsunari, Michiyo Honda, Kazuaki Nakano, Miki Maehara, Naomi Sugimoto, Mirina Kobayashi, Rieko Sakai, Yoshinori Asano, Masahito Watanabe, Kazuhiro Umeyama, and Hiroshi Nagashima
      Pancreas, Volume 44, Number 5, July 2015

      Angiotensin II accelerates mammary gland development independently of high blood pressure in pregnancyassociated hypertensive mice

      Kazuya Murata, Altansarnai Baasanjav, Chulwon Kwon, Misuzu Hashimoto, Junji Ishida & Akiyoshi Fukamizu
      Physiol Rep, 3 (9), 2015, e12542

      Serotonin 2C receptor contributes togender differences in stress-inducedhypophagia in aged mice

      Chihiro Yamada, Chiharu Sadakane, Miwa Nahata, Yayoi Saegusa, Koji Nakagawa, Naoto Okubo, Shunsuke Ohnishi, Tomohisa Hattori, Hiroshi Takeda
      Psychoneuroendocrinology (2015) 55, 81-93

      Prior attenuation of KiSS1/GPR54 signaling in the anteroventralperiventricular nucleus is a trigger for the delayed effect inducedby neonatal exposure to 17alpha-ethynylestradiol in female rats

      Ryohei Ichimura, Miwa Takahashi, Tomomi Morikawa, Kaoru Inoue, Jun Maeda, Kento Usuda, Makoto Yokosuka, Gen Watanabe, Midori Yoshida
      Reproductive Toxicology 51 (2015) 145-156

      Parturition failure in mice lacking Mamld1

      Mami Miyado, Kenji Miyado, Momori Katsumi, Kazuki Saito, Akihiro Nakamura, Daizou Shihara, Tsutomu Ogata & Maki Fukami
      Scientific Reports, 5:14705

      WRN protein as a novel erythroblast immunohistochemical marker with applications for the diagnosis of Werner syndrome [iPGell]

      Yoshito Sadahira & Takashi Sugihara & Hideyo Fujiwara & Hirotake Nishimura & Yoshimasa Suetsugu & Morishige Takeshita & Seiichi Okamura & Makoto Goto
      Virchows Arch, December 2014


      【2014】

      Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption

      Hiroki Yoshimatsu, Atsushi Yonezawa, Yoshiaki Yao, Kumiko Sugano, Shunsaku Nakagawa, Tomohiro Omura, and Kazuo Matsubara
      Am J Physiol Gastrointest Liver Physiol 306: G102-G110, 2014.

      Expression and in situ localization of GATA4, 5 and 6 mRNAs in ovine conceptuses and uterine endometria during the peri-implantation period

      Hanako BAI, Toshihiro SAKURAI, James D. GODKIN and Kazuhiko IMAKAWA
      Animal Science Journal (2014) 85, 388-394

      Tenomodulin regulatedthecompartmentsofembryonicandearly postnatal mousemassetermuscle

      Iwao Sato, Yoko Miwa, Setsuhiro Hara, Yutaka Fukuyama, Masataka Sunohara
      Annals of Anatomy196(2014)410-415

      The basic helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates Twist1 through an E-box element

      Masatoshi Suzuki, Fuyuki Sato, Ujjal K. Bhawal
      Biochemical and Biophysical Research Communications 455 (2014) 390-395

      Glutamic acid decarboxylase 1 alternative splicing isoforms: characterization, expression and quantification in the mouse brain

      Stefan Trifonov, Yuji Yamashita, Masahiko Kase, Masato Maruyama and Tetsuo Sugimoto
      BMC Neuroscience 2014, 15:114

      Repression of cathepsin E expression increases the risk of mammary carcinogenesis and links to poor prognosis in breast cancer

      Tomoyo Kawakubo, Atsushi Yasukochi, Tatsuya Toyama, Satoru Takahashi, Kuniaki Okamoto, Takayuki Tsukuba, Seiji Nakamura, Yasuhiko Ozaki, Koichi Nishigaki, Hiroko Yamashita and Kenji Yamamoto
      Carcinogenesis vol.35 no.3 pp.714-726, 2014

      Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

      Natsumi Maehara, Satoko Arai, Mayumi Mori, Yoshihiro Iwamura, Jun Kurokawa, Toshihiro Kai, Shunsuke Kusunoki, Kaori Taniguchi, Kazutaka Ikeda, Osamu Ohara, Ken-ichi Yamamura, and Toru Miyazaki
      Cell Reports 9, 61-74, October 9, 2014

      Effects of thalidomide on Fgf8, Bmp4 and Hoxa11 expression in the limb bud in Kbl:JW rabbit embryos

      Yoshinori Kawamura, Teruyoshi Yamashita, Toshiaki Yamauchi, Kiyoshi Matsumoto, and Keiichiro Sato
      Congenital Anomalies 2014; 54, 54-62

      Molecular pathogenesis of Spondylocheirodysplastic Ehlers-Danlos syndrome caused by mutant ZIP13 proteins

      Bum-Ho Bin, Shintaro Hojyo, Toshiaki Hosaka, Jinhyuk Bhin, Hiroki Kano, Tomohiro Miyai, Mariko Ikeda, Tomomi Kimura-Someya, Mikako Shirouzu, Eun-Gyung Cho, Kazuhisa Fukue, Taiho Kambe, Wakana Ohashi, Kyu-Han Kim, Juyeon Seo, Dong-Hwa Choi, Yeon-Ju Nam, Daehee Hwang, Ayako Fukunaka, Yoshio Fujitani, Shigeyuki Yokoyama, Andrea Superti-Furga, Shiro Ikegawa, Tae Ryong Lee, & Toshiyuki Fukada
      EMBO Molecular Medicine, May 2014

      Identification of a developmentally-regulated and psychostimulant-inducible novel rat gene mrt3 in the neocortex

      Naoki Yamamoto, Shin-ichiro Muraoka, Yasushi Kajii, Asami Umino, Toru Nishikawa
      European Neuropsychopharmacology(2014) 24, 1687-1697

      Oligo-astheno-teratozoospermia in mice lacking ORP4, a sterol-binding protein in the OSBP-related protein family

      Osamu Udagawa, Chizuru Ito, Narumi Ogonuki, Hiroyasu Sato, Shoken Lee, Pearlta Tripvanuntakul, Ikuyo Ichi, Yasunori Uchida, Taki Nishimura, Makoto Murakami, Atsuo Ogura, Takao Inoue, Kiyotaka Toshimori and Hiroyuki Arai
      Genes to Cells (2014) 19, 13-27

      The Leucine Twenty Homeobox (LEUTX) Gene, Which Lacks a Histone Acetyltransferase Domain, is Fused to KAT6A in Therapy-Related Acute Myeloid Leukemia with t(8;19)(p11;q13)

      Yoshiaki Chinen, Tomohiko Taki, Yasuhiko Tsutsumi, Satoru Kobayashi, Yosuke Matsumoto, Natsumi Sakamoto, Junya Kuroda, Shigeo Horiike, Kazuhiro Nishida, Hirofumi Ohno, Naokuni Uike, and Masafumi Taniwaki
      GENES, CHROMOSOMES & CANCER 53:299-308 (2014)

      Identification of a Chimeric Transcript formed by Intergenic Splicing of UbiE2 and Yghl1-4 in Mouse

      Ravi Nagganatha Suganthan, Sahi Vaidurya Pratap, Morita Eugene Hayato and Abe Shunnosuke
      International Research Journal of Biological Sciences Vol. 3(3), 52-59, March (2014)

      The N-terminal Arg Residue Is Essential for Autocatalytic Activation of a Lipopolysaccharide-responsive Protease Zymogen

      Yuki Kobayashi, Takafumi Shiga, Toshio Shibata, Miyuki Sako, Katsumi Maenaka, Takumi Koshiba, Hikaru Mizumura, Toshio Oda, and Shun-ichiro Kawabata
      THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 289, NO. 37, pp. 25987-25995, September 12, 2014

      Expression and localization of laminin 5, laminin 10, type IV collagen, and amelotin in adult murine gingiva

      Takashi Sawada, Takaki Yamazaki, Kazuko Shibayama, Kaido Kumazawa, Yoko Yamaguchi, Mitsuhiro Ohshima
      J Mol Hist (2014) 45:293-302

      Daidzein promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and improves glucose homeostasis in Type 2 diabetic model mice

      Sun Hee Cheong, Keisuke Furuhashi, Katsuki Ito, Masato Nagaoka, Takayuki Yonezawa, Yutaka Miura, Kazumi Yagasaki
      Journal of Nutritional Biochemistry 25 (2014) 136-143

      Phosphoproteome Analysis of Formalin-Fixed and Paraffin-Embedded Tissue Sections Mounted on Microscope Slides

      Masaki Wakabayashi, Hiroki Yoshihara, Takeshi Masuda, Mai Tsukahara, Naoyuki Sugiyama, and Yasushi Ishihama
      J. Proteome Res. 2014, 13, 915-924

      A mouse renin distal enhancer is essential for blood pressure homeostasis in BAC-rescued renin-null mutant mice

      Keiji Tanimoto, Sumiyo Kanafusa, Aki Ushiki, Hitomi Matsuzaki, Junji Ishida, Fumihiro Sugiyama, and Akiyoshi Fukamizu
      J Recept Signal Transduct Res, April 2014

      Intravesical Application of Rebamipide Promotes Urothelial Healing in a Rat Cystitis Model

      Yasuhito Funahashi, Masaki Yoshida, Tokunori Yamamoto, Tsuyoshi Majima, Shun Takai and Momokazu Gotoh
      THE JOURNAL OF UROLOGY, Vol. 192, 1864-1870, December 2014

      Antihyperglycemic effect of equol, a daidzein derivative, in cultured L6 myocytes and ob/ob mice

      Sun Hee Cheong, Keisuke Furuhashi, Katsuki Ito, Masato Nagaoka, Takayuki Yonezawa, Yutaka Miura1 and Kazumi Yagasaki
      Mol. Nutr. Food Res. 2014, 58, 267-277

      Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection

      Kotaro Kiga, Hitomi Mimuro, Masato Suzuki, Aya Shinozaki-Ushiku, Taira Kobayashi, Takahito Sanada, Minsoo Kim, Michinaga Ogawa, Yuka W. Iwasaki, Hiroyuki Kayo, Yoko Fukuda-Yuzawa, Masakazu Yashiro, Masashi Fukayama, Taro Fukao & Chihiro Sasakawa
      NATURE COMMUNICATIONS, 5:4497, 2014

      Urocortin1-induced anorexia is regulated by activation of theserotonin 2C receptor in the brain

      Yumi Harada, Kiyoshige Takayama, Shoki Ro, Mitsuko Ochiai, Masamichi Noguchi, Seiichi Iizuka, Tomohisa Hattori, Koji Yakabi
      Peptides 51 (2014) 139-144

      Age-dependent kainate sensitivity in heterozygous rolling Nagoya Cav2.1 channel mutant mice

      Tae Yeon Kim, Takuro Yoshimoto, Yo Aoyama, Kimie Niimi, Eiki Takahashi, Chitoshi Itakura
      Pharmacology, Biochemistry and Behavior 124 (2014) 250-259

      Pseudomonas-Derived Ceramidase Induces Production of Inflammatory Mediators from Human Keratinocytes via Sphingosine-1-Phosphate

      Ami Oizumi, Hitoshi Nakayama, Nozomu Okino, Chihiro Iwahara, Katsunari Kina, Ryo Matsumoto, Hideoki Ogawa, Kenji Takamori, Makoto Ito, Yasushi Suga, Kazuhisa Iwabuchi
      PLoS ONE 9(2): e89402

      Fomiroid A, a Novel Compound from the Mushroom Fomitopsis nigra, Inhibits NPC1L1-Mediated Cholesterol Uptake via a Mode of Action Distinct from That of Ezetimibe

      Tomohiro Chiba, Tsuyoshi Sakurada, Rie Watanabe, Kohji Yamaguchi, Yasuhisa Kimura, Noriyuki Kioka, Hirokazu Kawagishi, Michinori Matsuo, Kazumitsu Ueda
      PLoS ONE 9(12): e116162

      Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development

      Tomohiro Miyai, Shintaro Hojyo, Tomokatsu Ikawa, Masami Kawamura, Tarou Irie, Hideki Ogura, Atsushi Hijikata, Bum-Ho Bin, Takuwa Yasuda, Hiroshi Kitamura, Manabu Nakayama, Osamu Ohara, Hisahiro Yoshida, Haruhiko Koseki, Kenji Mishima, and Toshiyuki Fukada
      11780-11785 | PNAS | August 12, 2014 | vol. 111 | no. 32

      Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength

      Shintaro Hojyo, Tomohiro Miyai, Hitomi Fujishiro, Masami Kawamura, Takuwa Yasuda, Atsushi Hijikata, Bum-Ho Bin, Tarou Irie, Junichi Tanaka, Toru Atsumi, Masaaki Murakami, Manabu Nakayama, Osamu Ohara, Seiichiro Himeno, Hisahiro Yoshida, Haruhiko Koseki, Tomokatsu Ikawa, Kenji Mishima, and Toshiyuki Fukada
      11786-11791 | PNAS | August 12, 2014 | vol. 111 | no. 32

      Involvement of VCAM1 in the bovine conceptus adhesion to the uterine endometrium

      Rulan Bai, Hanako Bai, Mariko Kuse, Atsushi Ideta, Yoshito Aoyagi, Hiroshi Fujiwara, Kiyoshi Okuda, Kazuhiko Imakawa and Toshihiro Sakurai
      Reproduction (2014) 148 119?127

      Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer

      Masahiro Yasunaga & Yasuhiro Matsumura
      SCIENTIFIC REPORTS | 4 : 4852, 2014

      2-(4-Hydroxy-3-methoxyphenyl)-benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP

      Hiromi Hiyoshi, Natsuka Goto, Mai Tsuchiya, Keisuke Iida, Yuka Nakajima, Naoya Hirata, Yasunari Kanda, Kazuo Nagasawa & Junn Yanagisawa
      SCIENTIFIC REPORTS | 4 : 7095, 2014


      【2013】

      Expression and localization of taste receptor genes in the vallate papillae of rats: effect of zinc deficiency

      Atsuo Ikeda, Hiroki Sekine, Kyoichi Takao and Minoru Ikeda
      Acta Oto-Laryngologica, 2013 133(9); 957-964

      Analysis of ischemic neuronal injury in Cav2.1 channel α1 subunit mutant mice

      Xiaoli Tian, Ying Zhou, Linghan Gao, Guang He, Weizhong Jiang, Weidong Li, Eiki Takahashi
      Biochemical and Biophysical Research Communications, 2013 434(1); 60-64

      Mammalian galectins bind Galactoseβ1-4Fucose disaccharide, a unique structural component of protostomial N-type glycoproteins

      Tomoharu Takeuchi, Mayumi Tamura, Kazusa Nishiyama, Jun Iwaki, Jun Hirabayashi, Hideyo Takahashi, Hideaki Natsugari, Yoichiro Arata, Ken-ichi Kasai
      Biochemical and Biophysical Research Communications, 2013 436(3); 509-513

      Secure Splenic Delivery of Plasmid DNA and Its Application to DNA Vaccine

      Tomoaki Kurosaki, Yukinobu Kodama, Takahiro Muro, Norihide Higuchi, Tadahiro Nakamura, Takashi Kitahara, Mana Miyakoda, Katsuyuki Yui, and Hitoshi Sasaki
      Biol. Pharm. Bull. 36(11) 1800-1806 (2013)

      The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos

      Shuji Ueda, Becky Tu-Sekine, Minoru Yamanoue, Daniel M Raben and Yasuhito Shirai
      BMC Developmental Biology 2013, 13:35

      Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells

      Satoko Arai, Natsumi Maehara, Yoshihiro Iwamura, Shin-ichiro Honda, Katsuhiko Nakashima, Toshihiro Kai, Masato Ogishi, Kumiko Morita, Jun Kurokawa, Mayumi Mori, Yuji Motoi, Kensuke Miyake, Nobuyuki Matsuhashi, Ken-ichi Yamamura, Osamu Ohara, Akira Shibuya, Edward K. Wakeland, Quan-Zhen Li, and Toru Miyazaki
      Cell Reports, 2013 3(4); 1187-1198

      CD4 and CD8 homologues in Japanese flounder, Paralichthys olivaceus: Differences in the expressions and localizations of CD4-1, CD4-2, CD8α and CD8β

      Goshi Kato, Kana Goto, Ikuyo Akune, Shoichiro Aoka, Hidehiro Kondo, Ikuo Hirono
      Developmental and Comparative Immunology, 2013 39(3); 293-301

      The role of small proliferative adipocytes in the development of obesity: Comparison between Otsuka Long-Evans Tokushima Fatty (OLETF) rats and non-obese Long-Evans Tokushima Otsuka (LETO) rats [iPGell]

      Takayuki Hanamoto, Kazuo Kajita, Ichiro Mori, Takahide Ikeda, Kei Fujioka, Masahiro Yamauchi, Hideyuki Okada, Taro Usui, Noriko Takahashi, Yoshihiko Kitada, Koichiro Taguchi, Toshiko Kajita, Yoshihiro Uno, Hiroyuki Morita and Tatsuo Ishizuka
      Endocrine Journal 2013, 60 (8), 1001-1011

      Tissue-specific expression of the pheromone gland-specific fatty acyl reductase gene in Ostrinia scapulalis

      Binu Antony and Yukio Ishikawa
      Entomologia Experimentalis et Applicata, 2013; 1-5

      Reduced responsiveness of kisspeptin neurons to estrogenic positive feedback associated with age-related disappearance of LH surge in middle-age female rats

      Misawa Niki Ishii, Kiyoshi Matsumoto, Hisanori Matsui, Nobuyuki Seki, Hirokazu Matsumoto, Kaori Ishikawa, Fumio Chatani, Gen Watanabe, Kazuyoshi Taya
      General and Comparative Endocrinology, 2013 193; 121-129

      Expression pattern of zinc-finger transcription factor Odd-skipped related 2 in murine development and neonatal stage

      Shinji Kawai, Ikumi Michikami, Jirouta Kitagaki, Ei Hashino, Atsuo Amano
      Gene Expression Patterns, 2013 13(8); 372-376

      FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration

      Hinako M. Takase, Tohru Itoh, Seitaro Ino, Ting Wang, Takehiko Koji, Shizuo Akira, Yasuhiro Takikawa, and Atsushi Miyajima
      GENES & DEVELOPMENT, 2013 27(2); 169-181

      MARCH7 E3 ubiquitin ligase is highly expressed in developing spermatids of rats and its possible involvement in head and tail formation

      Boqiang Zhao, Kunitoshi Ito, Prasanna Vasudevan Iyengar, Shigehisa Hirose, Nobuhiro Nakamura
      Histochemistry and Cell Biology, 2013 139(3); 447-460

      Tissue plasminogen activator deficiency promotes early phase regeneration in the olfactory epithelium after bulbectomy

      Nobuko Makino, Seiji Madoiwa, Tsukasa Ohmori, Kazuo Katoh, Shigeo Ookawara, Takeharu Kanazawa, Osamu Matsuo, Masumi Ichikawa, Jun Mimuro, Keiichi Ichimura and Yoichi Sakata
      International Forum of Allergy & Rhinology, 2013 3(6); 458-467

      Bacteriocin Protein BacL1 of Enterococcus faecalis Is a Peptidoglycan D-Isoglutamyl-L-lysine Endopeptidase

      Jun Kurushima, Ikue Hayashi, Motoyuki Sugai, and Haruyoshi Tomita
      THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 288, NO. 52, pp. 36915-36925, December 27, 2013

      Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation

      Sunao Takeshita, Toshio Fumoto, Kazuhiko Matsuoka, Kyoung-ae Park, Hiroyuki Aburatani, Shigeaki Kato, Masako Ito and Kyoji Ikeda
      The Journal of Clinical Investigation, 2013 [Epub ahead of print]

      Functional, Anatomical, and Neurochemical Differentiation of Medial Preoptic Area Subregions in Relation to Maternal Behavior in the Mouse

      Yousuke Tsuneoka, Teppo Maruyama, Sachine Yoshida, Katsuhiko Nishimori, Tadafumi Kato, Michael Numan and Kumi O. Kuroda
      The Journal of Comparative Neurology, 2013 521(7); 1633-1663

      Identification, Characterization, and Expression of Dentin Matrix Protein 1 Gene in Xenopus laevis

      TOMOKO YONEKURA, HIROMI HOMMA, ATSUO SAKURAI, MITSUKO MORIGUCHI, YASUO MIAKE, SATORU TOYOSAWA, AND SEIKOU SHINTANI
      J. Exp. Zool. (Mol. Dev. Evol.) 320B:525-537, 2013

      Th1/Th17-Mediated Interstitial Pneumonia in Chronic Colitis Mice Independent of Intestinal Microbiota

      Yasuhiro Nemoto, Takanori Kanai, Masahiro Takahara, Shigeru Oshima, Ryuichi Okamoto, Kiichiro Tsuchiya, Satoshi Matsumoto and Mamoru Watanabe
      The Journal of Immunology, 2013 190(12); 6616-6625

      Paraneoplastic cerebellar degeneration associated with an onconeural antibody against creatine kinase, brain-type

      Syuichi Tetsuka, Kaoru Tominaga, Eriko Ohta, Kenji Kuroiwa, Eiji Sakashita, Katsumi Kasashima, Toshiro Hamamoto, Michito Namekawa, MitsuyaMorita, ShinsukeNatsui, TatsuoMorita, Keiko Tanaka, Yoshihisa Takiyama, Imaharu Nakano, Hitoshi Endo
      Journal of the Neurological Sciences 335 (2013) 48-57

      Age- and sex-dependent DNA hypomethylation controlled by growth hormone in mouse liver

      Masaki Takasugi, Koji Hayakawa, Daisuke Arai, Kunio Shiota
      Mechanisms of Ageing and Development, 2013 134(7-8); 331-337

      Transcription factor Spi-B -dependent and -independent pathways for the development of Peyer’s patch M cells

      S Sato, S Kaneto, N Shibata, Y Takahashi, H Okura, Y Yuki, J Kunisawa and H Kiyono
      Mucosal Immunology, 2013 6(4); 838-846

      Cuprizone short-term exposure: Astrocytic IL-6 activation and behavioral changes relevant to psychosis

      Tomoaki Tezuka, Makoto Tamura, Mari A. Kondo, Masaki Sakaue, Kinya Okada, Kana Takemoto, Atsushi Fukunari, Keiko Miwa, Hiromitsu Ohzeki, Shin-ichi Kano, Hiroshi Yasumatsu, Akira Sawa, Yasushi Kajii
      Neurobiology of Disease, 2013 59; 63-68

      SGLT5 Reabsorbs Fructose in the Kidney but Its Deficiency Paradoxically Exacerbates Hepatic Steatosis Induced by Fructose

      Taku Fukuzawa, Masanori Fukazawa, Otoya Ueda, Hideaki Shimada, Aki Kito, Mami Kakefuda, Yosuke Kawase, Naoko A. Wada, Chisato Goto, Naoshi Fukushima, Kou-ichi Jishage, Kiyofumi Honda, George L. King, Yoshiki Kawabe

      PLoS ONE, 2013 8(2); e56681

      Microarray Analysis of Novel Candidate Genes Responsible for Glucose-Stimulated Insulin Secretion in Mouse Pancreatic β Cell Line MIN6

      Eiji Yamato, Fumi Tashiro, Jun-ichi Miyazaki
      PLoS ONE, 2013 8(4); e61211

      Regulation of the Epithelial Adhesion Molecule CEACAM1 Is Important for Palate Formation

      Junko Mima, Aya Koshino, Kyoko Oka, Hitoshi Uchida, Yohki Hieda, Kanji Nohara, Mikihiko Kogo, Yang Chai, Takayoshi Sakai
      PLoS ONE 8(4): e61653

      Serotonin 2C receptor antagonism ameliorates novelty-induced hypophagia in aged mice

      Miwa Nahata, Shuichi Muto, Koji Nakagawa, Shunsuke Ohnishi, Chiharu Sadakane, Yayoi Saegusa, Seiichi Iizuka, Tomohisa Hattori, Masahiro Asaka, Hiroshi Takeda
      Psychoneuroendocrinology (2013) 38, 2051-2064


      【2012】

      Low-Dose-Rate, Low-Dose Irradiation Delays Neurodegeneration in a Model of Retinitis Pigmentosa

      Atsushi Otani, Hiroshi Kojima, Congrong Guo, Akio Oishi, and Nagahisa Yoshimura
      The American Journal of Pathology 2012 180(1); 328-336

      An anxiogenic drug, FG 7142, induced an increase in mRNA of Btg2 and Adamts1 in the hippocampus of adult mice

      Akeo Kurumaji and Toru Nishikawa
      Behavioral and Brain Functions, 2012 8; 43

      Histological demonstration of glucose transporters, fructose-1,6-bisphosphatase, and glycogen in gas gland cells of the swimbladder: Is a metabolic futile cycle operating?

      Keijiro Munakata, Kayoko Ookata, Hiroyuki Doi, Otto Baba, Tatsuo Terashima, Shigehisa Hirose, Akira Kato
      Biochemical and Biophysical Research Communications, 2012 417(1); 564-569

      Piceatannol, a resveratrol derivative, promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and suppresses blood glucose levels in type 2 diabetic model db/db mice

      Miki Minakawa, Yutaka Miura, Kazumi Yagasaki
      Biochemical and Biophysical Research Communications, 2012 422(3); 469-475

      Downregulation of N-methyl-d-aspartate receptor ζ1 subunit (GluN1) gene in inferior colliculus with aging

      Yasunori Osumi, Seiji Bruce Shibata, Seiji Kanda, Masao Yagi, Hisashi Ooka, Takashi Shimano, Mikiya Asako, Kohei Kawamoto, Hiromichi Kuriyama, Toshiya Inoue, Toshimasa Nishiyama, Toshio Yamashita, Koichi Tomoda
      Brain Research, 2012 1454; 23-32

       

      A Genome-Wide Expression Profile of Adrenocortical Cells in Knockout Mice Lacking Steroidogenic Acute Regulatory Protein

      Tomohiro Ishii, Toshikatsu Mitsui, Sadafumi Suzuki, Yumi Matsuzaki, and Tomonobu Hasegawa
      Endocrinology, 2012 153(6); 2714-2723

      Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis

      Hiroyuki Murota, Mayuko Izumi, Mostafa I. A. Abd El-Latif, Megumi Nishioka, Mika Terao, Mamori Tani, Saki Matsui, Shigetoshi Sano, and Ichiro Katayama
      The Journal of allergy and clinical immunology, 2012 130; 671-682

      Roles of heparan sulfate sulfation in dentinogenesis

      Satoru Hayano, Hiroshi Kurosaka, Takeshi Yanagita, Ina Kalus, Fabian Milz, Yoshihito Ishihara, Md. Nurul Islam, Noriaki Kawanabe, Masahiro Saito, Hiroshi Kamioka, Taiji Adachi, Thomas Dierks and Takashi Yamashiro
      The Journal of Biological Chemistry, 2012 287(15); 12217-12229

      The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

      Shigetomo Fukuhara, Szandor Simmons, Shunsuke Kawamura, Asuka Inoue, Yasuko Orba, Takeshi Tokudome, Yuji Sunden, Yuji Arai, Kazumasa Moriwaki, Junji Ishida, Akiyoshi Uemura, Hiroshi Kiyonari, Takaya Abe, Akiyoshi Fukamizu, Masanori Hirashima, Hirofumi Sawa, Junken Aoki, Masaru Ishii, and Naoki Mochizuki
      The Journal of Clinical Investigation, 2012 122(4); 1416-1426

      Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells

      Hitomi Fujishiro, Yu Yano, Yukina Takada, Maya Tanihara and Seiichiro Himeno
      Metallomics, 2012 4; 700-708

      Suppression of pleiotrophic phenotypes of Burkholderia multivorans fur mutant by oxyR mutation

      Akane Kimura, Satoshi Yuhara, Yoshiyuki Ohtsubo, Yuji Nagata, and Masataka Tsuda
      Microbiology, 2012 158(Pt 5); 1284-1293

      Expression of GATA1 in the Ovine Conceptus and Endometrium During the Peri-Attachment Period

      Hanako Bai, Toshihiro Sakurai, Toshihiro Konno, Atsushi Ideta, Yoshito Aoyagi, James D. Godkin, and Kazuhiko Imakawa
      Molecular Reproduction & Development, 2012 79(1); 64-73

      Coexistence of fibrotic and chondrogenic process in the capsule of idiopathic frozen shoulders

      Y. Hagiwara, A. Ando, Y. Onoda, T. Takemura, T. Minowa, N. Hanagata, M. Tsuchiya, T. Watanabe, E. Chimoto, H. Suda, N. Takahashi, H. Sugaya, Y. Saijo, E. Itoi
      Osteoarthritis and Catilage, 2012 20(3); 241-249

      Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells

      Masaki Mori, Hironori Nakagami, Gerardo Rodriguez-Araujo, Keisuke Nimura, Yasufumi Kaneda
      PLoS Biology, 2012 10(4); e1001314

      O2-Filled Swimbladder Employs Monocarboxylate Transporters for the Generation of O2 by Lactate-Induced Root Effect Hemoglobin

      Takahiro Umezawa, Akira Kato, Maho Ogoshi, Kayoko Ookata, Keijiro Munakata, Yoko Yamamoto, Zinia Islam, Hiroyuki Doi, Michael F. Romero, Shigehisa Hirose
      PLoS ONE, 2012 7(4); e34579

      Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells

      Yu Hisano, Naoki Kobayashi, Akihito Yamaguchi, Tsuyoshi Nishi
      PLoS ONE, 2012 7(6); e38941

      Binding of transcription factor activating protein 2γ on the 5′ -proximal promoter region of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B

      Yuki Nakaya, Sayumi Shimode, Takeshi Kobayashi, Kazuhiko Imakawa and Takayuki Miyazawa
      Xenotransplantation, 2012 19(3); 177-185


      【2011】

      Urocortin 1 reduces food intake and ghrelin secretion via CRF2 receptors

      Koji Yakabi, Masamichi Noguchi, Shino Ohno, Shoki Ro, Tsuneko Onouchi, Mitsuko Ochiai, Hidehiko Takabayashi, Kiyoshige Takayama, Yumi Harada, Chiharu Sadakane, and Tomohisa Hattori
      American Journal of Physiology – Endocrinology and Metabolism, 2011 301(1); E72-E82

      Differential expression of Na+-Cl cotransporter and Na+-K+-Cl cotransporter 2 in the distal nephrons of euryhaline and seawater pufferfishes

      Akira Kato, Takayuki Muro, Yuuri Kimura, Shanshan Li, Zinia Islam, Maho Ogoshi, Hiroyuki Doi, and Shigehisa Hirose
      American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, 2011 300(2); R284-R297

      Characterization of porcine autism susceptibility candidate 2 as a candidate gene for the number of corpora lutea in pigs

      Shuji Sato, Takeshi Hayashi, Eiji Kobayashi
      Animal Reproduction Science, 2011 126(3-4); 211-220

      The role of cathepsin E in terminal differentiation of keratinocytes

      Tomoyo Kawakubo, Atsushi Yasukochi, Kuniaki Okamoto, Yoshiko Okamoto, Seiji Nakamura and Kenji Yamamoto
      Biological Chemistry, 2011 392(6); 571-585

      FXYD6, a Na,K-ATPase Regulator, Is Expressed in Type II Taste Cells

      Yoichiro Shindo, Kana Morishita, Eiichi Kotake, Hirohito Miura, Piero Carninci, Jun Kawai, Yoshihide Hayashizaki, Akihiro Hino, Tomomasa Kanda, and Yuko Kusakabe
      Bioscience, Biotechnology, and Biochemistry, 2011 75(6); 1061-1066

      Granulocyte colony-stimulating factor attenuates oxidative stress-induced apoptosis in vascular endothelial cells and exhibits functional and morphologic protective effect in oxygen-induced retinopathy

      Hiroshi Kojima, Atsushi Otani, Akio Oishi, Yukiko Makiyama, Satoko Nakagawa, and Nagahisa Yoshimura
      Blood, 2011 117(3); 1091-1100

      Organic Anion Transporter 3 Mediates the Efflux Transport of an Amphipathic Organic Anion, Dehydroepiandrosterone Sulfate, across the Blood-Brain Barrier in Mice

      Mari Miyajima, Hiroyuki Kusuhara, Miki Fujishima, Yasuhisa Adachi, and Yuichi Sugiyama
      Drug Metabolism and Disposition, 2011 39(5); 814-819

      Blocking of sodium and potassium ion-dependent adenosine triphosphatase-α1 with ouabain and vanadate suppresses cell-cell fusion during RANKL-mediated osteoclastogenesis

      Seicho Makihira, Hiroki Nikawa, Mikihito Kajiya, Toshihisa Kawai, Yuichi Mine, Eduardo Kosaka, Marcelo J.B. Silva, Kei Tobiume, Yoshihiro Terada
      European Journal of Pharmacology, 2011 670(2-3); 409-418

      Full-Length Sequence of Mouse Acupuncture-Induced 1-L (Aig1l ) Gene Including Its Transcriptional Start Site

      Mika Ohta, Aki Sugano, Shuji Goto, Surini Yusoff, Yushi Hirota, Kotaro Funakoshi, Kenji Miura, Eiichi Maeda, Nobuo Takaoka, Nobuko Sato, Hiroshi Ishizuka, Naoki Arizono, Hisahide Nishio, and Yutaka Takaoka
      Evidence-Based Complementary and Alternative Medicine, 2011; ID: 249280

      High expression levels of Chitinase Genes in Streptomyces coelicolor A3(2) Grown in Soil

      Behnam Nazari, Akihiro Saito, Michihiko Kobayashi, Kiyotaka Miyashita, Youg Wang and Takeshi Fujii
      FEMS Microbiology Ecology, 2011 77(3); 623-635

      Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice

      Nobutaka Hanagata, Xianglan Li, Hiromi Morita, Taro Takemura, Jie Li, Takashi Minowa
      Journal of Bone and Mineral Metabolism, 2011 29(3); 279-290

      Cloning and characterization of the osteoarthritis-associated gene DVWA

      Masahiro Nakajima, Yoshinari Miyamoto, Shiro Ikegawa
      Journal of Bone and Mineral Metabolism, 2011 29(3); 300-308

      Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice

      Mayumi Mori, Miwako Kitazume, Rui Ose, Jun Kurokawa, Kaori Koga, Yutaka Osuga, Satoko Arai, and Toru Miyazaki
      The Journal of Clinical Investigation, 2011 121(1); 318-327

      The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells

      Shuichiro Takashima, Masanori Kadowaki, Kazutoshi Aoyama, Motoko Koyama, Takeshi Oshima, Kazuma Tomizuka, Koichi Akashi, and Takanori Teshima
      The Journal of Experimental Medicine, 2011 208(2); 285-294

      A genome-wide association study identifies RNF213 as the first Moyamoya disease gene

      Fumiaki Kamada, Yoko Aoki, Ayumi Narisawa, Yu Abe, Shoko Komatsuzaki, Atsuo Kikuchi, Junko Kanno, Tetsuya Niihori, Masao Ono, Naoto Ishii, Yuji Owada, Miki Fujimura, Yoichi Mashimo, Yoichi Suzuki, Akira Hata, Shigeru Tsuchiya, Teiji Tominaga, Yoichi Matsubara and Shigeo Kure
      Journal of Human Genetics, 2011 56(1); 34-40

      Inositol 1,4,5-trisphosphate receptors are essential for the development of the second heart field

      Maki Nakazawa, Keiko Uchida, Megumi Aramaki, Kazuki Kodo, Chihiro Yamagishi, Takao Takahashi, Katsuhiko Mikoshiba, Hiroyuki Yamagishi
      Journal of Molecular and Cellular Cardiology, 2011 51(1); 58-66

      Antidepressant-like behavior in brain-specific angiogenesis inhibitor 2-deficient mice

      Daisuke Okajima, Gen Kudo, Hiroshi Yokota
      The Journal of Physiological Sciences, 2011 61(1); 47-54

      DNA Methylation-dependent Modulator of Gsg2/Haspin Gene Expression

      Shun Sato, Chiaki Maeda, Naka Hattori, Shintaro Yagi, Satoshi Tanaka, Kunio Shiota
      Journal of Reproduction and Development, 2011 57(4); 526-533

      Molecular and genetic features of zinc transporters in physiology and pathogenesis

      Toshiyuki Fukada and Taiho Kambe
      Metallomics, 2011 3(7); 662-674 (review)

      Essential Roles of ECAT15-2/Dppa2 in Functional Lung Development

      Tomonori Nakamura, Masato Nakagawa, Tomoko Ichisaka, Arufumi Shiota, and Shinya Yamanaka
      Molecular and Cellular Biology, 2011 31(21); 4366-4378

      Urinary angiotensin-converting enzyme 2 in patients with CKD

      Sonoo Mizuiri, Toshiyuki Aoki, Hiromichi Hemmi, Michitsune Arita, Ken Sakai and Atsushi Aikawa
      Nephrology, 2011 16; 567-572

      MicroRNA 130 family regulates the hypoxia response signal through the P-body protein DDX6

      Ken Saito, Eisaku Kondo and Masayuki Matsushita
      Nucleic Acids Research, 2011 39(14); 6086-6099

      The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth

      Shintaro Hojyo, Toshiyuki Fukada, Shinji Shimoda, Wakana Ohashi, Bum-Ho Bin, Haruhiko Koseki, Toshio Hirano
      PLoS ONE, 2011 6(3); e18059

      Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue

      Jun Kurokawa, Hiromichi Nagano, Osamu Ohara, Naoto Kubota, Takashi Kadowaki, Satoko Arai, and Toru Miyazaki
      Proceedings of the National Academy of Sciences of the USA, 2011 108(29); 12072-12077


      【2010】

      Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats

      Kumiko Nishihara, Satohiro Masuda, Shunsaku Nakagawa, Atsushi Yonezawa, Takaharu Ichimura, Joseph V. Bonventre, and Ken-ichi Inui
      American Journal of Physiology – Renal Physiology, 2010 298(4); F923-F934

      Direct repression of Sonic Hedgehog expression in the stomach by Cdx2 leads to intestinal transformation

      Hiroyuki Mutoh, Hiroko Hayakawa, Miho Sashikawa, Hirotsugu Sakamoto and Kentaro Sugano
      Biochemical Journal (Disease), 2010 427(3); 423-434

      LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis

      Hayakazu Sumida, Kyoko Noguchi, Yasuyuki Kihara, Manabu Abe, Keisuke Yanagida, Fumie Hamano, Shinichi Sato, Kunihiko Tamaki, Yasuyuki Morishita, Mitsunobu R. Kano, Caname Iwata, Kohei Miyazono, Kenji Sakimura, Takao Shimizu, and Satoshi Ishii
      Blood, 2010 116(23); 5060-5070

      Macrophage-Derived AIM Is Endocytosed into Adipocytes and Decreases Lipid Droplets via Inhibition of Fatty Acid Synthase Activity

      Jun Kurokawa, Satoko Arai, Katsuhiko Nakashima, Hiromichi Nagano, Akemi Nishijima, Keishi Miyata, Rui Ose, Mayumi Mori, Naoto Kubota, Takashi Kadowaki, Yuichi Oike, Hisashi Koga, Maria Febbraio, Toshihiko Iwanaga, and Toru Miyazaki
      Cell Metabolism, 2010 11(6); 479-492

      Functional Characterization of Mouse Organic Anion Transporting Peptide 1a4 in the Uptake and Efflux of Drugs Across the Blood-Brain Barrier

      Atsushi Ose, Hiroyuki Kusuhara, Chihiro Endo, Kimio Tohyama, Mari Miyajima, Satoshi Kitamura, and Yuichi Sugiyama
      Drug Metabolism and Disposition, 2010 38(1); 168-176

      Tumor necrosis factor-α processing inhibitor-1 inhibits skin fibrosis in a bleomycin-induced murine model of scleroderma

      Mika Terao, Hiroyuki Murota, Shun Kitaba and Ichiro Katayama
      Experimental Dermatology, 2010 19(1); 38-43

      A nonsense mutation in Gnat1, encoding the a subunit of rod transducin, in spontaneous mouse models of retinal dysfunction

      Makoto Miyamoto, Masami Aoki, Kazuko Hirai, Shinji Sugimoto, Kazuya Kawasaki, Ryoetsu Imai
      Experimental Eye Research, 2010 90(1); 63-69

      Identification of zebrafish Fxyd11a protein that is highly expressed in ion-transporting epithelium of the gill and skin and its possible role in ion homeostasis

      Kaori Saito, Nobuhiro Nakamura, Yusuke Ito, Kazuyuki Hoshijima, Masahiro Esaki, Boqiang Zhao and Shigehisa Hirose
      Frontiers in Physiology, 2010 1; 129

      Maternal-effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal-zygotic stage transition

      Fumi Tashiro, Masami Kanai-Azuma, Satsuki Miyazaki, Masahiro Kato, Tomofumi Tanaka, Shuichi Toyoda, Eiji Yamato, Hayato Kawakami, Tatsushi Miyazaki and Jun-Ichi Miyazaki
      Genes to Cells, 2010 15(8); 813-828

      Molecular characterization and expression of laccase genes in the salivary glands of the green rice leafhopper, Nephotettix cincticeps (Hemiptera: Cicadellidae)

      Makoto Hattori, Kazuko Tsuchihara, Hiroaki Noda, Hirosato Konishi, Yasumori Tamura, Tetsuro Shinoda, Masatoshi Nakamura, Tsuyoshi Hasegawa
      Insect Biochemistry & Molecular Biology, 2010 40(4); 331-338

      Rhesus Glycoprotein P2 (Rhp2) Is a Novel Member of the Rh Family of Ammonia Transporters Highly Expressed in Shark Kidney

      Tsutomu Nakada, Connie M. Westhoff, Yoko Yamaguchi, Susumu Hyodo, Xiaojin Li, Takayuki Muro, Akira Kato, Nobuhiro Nakamura, and Shigehisa Hirose
      The Journal of Biological Chemistry, 2010 285(4); 2653-2664

      Estrogen Down-regulation of the Scx Gene Is Mediated by the Opposing Strand-overlapping Gene Bop1

      Yukitomo Arao, Karen Carpenter, Sylvia Hewitt, and Kenneth S. Korach
      The Journal of Biological Chemistry, 2010 285(7); 4806-4814

      Group X phospholipase A2 is released during sperm acrosome reaction and controls fertility outcome in mice

      Jessica Escoffier, Ikram Jemel, Akemi Tanemoto, Yoshitaka Taketomi, Christine Payre, Christelle Coatrieux, Hiroyasu Sato, Kei Yamamoto, Seiko Masuda, Karin Pernet-Gallay, Virginie Pierre, Shuntaro Hara, Makoto Murakami, Michel De Waard, Gerard Lambeau, and Christophe Arnoult
      The Journal of Clinical Investigation, 2010 120(5); 1415-1428

      Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2

      Takuto Hideyama, Takenari Yamashita, Takeshi Suzuki, Shoji Tsuji, Miyoko Higuchi, Peter H. Seeburg, Ryosuke Takahashi, Hidemi Misawa, and Shin Kwak
      The Journal of Neuroscience, 2010 30(36); 11917-11925

      Genome-wide Association Study of Normal Tension Glaucoma: Common Variants in SRBD1 and ELOVL5 Contribute to Disease Susceptibility

      The Writing Committee fot the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society
      Ophthalmology, 2010 117(7); 1331-1338

      Role of PAF Receptor in Proinflammatory Cytokine Expression in the Dorsal Root Ganglion and Tactile Allodynia in a Rodent Model of Neuropathic Pain

      Shigeo Hasegawa, Yuta Kohro, Miho Shiratori, Satoshi Ishii, Takao Shimizu, Makoto Tsuda, Kazuhide Inoue
      PLoS ONE, 2010 5(5); e10467

      xCT deficiency accelerates chemically induced tumorigenesis

      Ami Nabeyama, Ai Kurita, Kenichi Asano, Yasunobu Miyake, Takuwa Yasuda, Ikuo Miura, Gen Nishitai, Satoko Arakawa, Shigeomi Shimizu, Shigeharu Wakana, Hisahiro Yoshida, and Masato Tanaka
      Proceedings of the National Academy of Sciences of the USA, 2010 107(14); 6436-6441


      【2009】

      3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

      Norihiro Shibuya, Makiko Tanaka, Mikiharu Yoshida, Yuki Ogasawara, Tadayasu Togawa, Kazuyuki Ishii, and Hideo Kimura
      Antioxidants & Redox Signaling, 2009 11(4); 703-714

      Identification of novel endogenous antisense transcripts by DNA microarray analysis targeting complementary strand of annotated genes

      Koji Numata, Yuko Osada, Yuki Okada, Rintaro Saito, Noriko Hiraiwa, Hajime Nakaoka, Naoyuki Yamamoto, Kazufumi Watanabe, Kazue Okubo, Chihiro Kohama, Akio Kanai, Kuniya Abe and Hidenori Kiyosawa
      BMC Genomics, 2009 10; 392

      Abd-B suppresses lepidopteran proleg development in posterior abdomen

      Shuichiro Tomita , Atsumi Kikuchi
      Developmental Biology, 2009 328(2); 403-409

      New Approach for M-Cell-Specific Molecules Screening by Comprehensive Transcriptome Analysis

      Gaku Nakato, Shinji Fukuda, Koji Hase, Ryo Goitsuka, Max D. Cooper, and Hiroshi Ohno
      DNA Research, 2009 16(4); 227-235

      ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis

      Takayuki Iriyama, Kohsuke Takeda, Hiromi Nakamura, Yoshifumi Morimoto, Takumi Kuroiwa, Junya Mizukami, Tsuyoshi Umeda, Takuya Noguchi, Isao Naguro, Hideki Nishitoh, Kaoru Saegusa, Kei Tobiume, Toshiki Homma, Yutaka Shimada, Hitoshi Tsuda, Satoshi Aiko, Issei Imoto, Johji Inazawa, Kazuhiro Chida, Yoshimasa Kamei, Shiro Kozuma, Yuji Taketani, Atsushi Matsuzawa and Hidenori Ichijo
      The EMBO Journal, 2009 28(7); 843-853

      Effect of dioxins on regulation of tyrosine hydroxylase gene expression by aryl hydrocarbon receptor: a neurotoxicology study

      Eiichi Akahoshi, Seiko Yoshimura, Saeko Uruno and Mitsuko Ishihara-Sugano
      Environmental Health, 2009 8; 24

      Unique alternative translation from two open reading frames on Acpin1 mRNA yields an acrosomal protein and a salivary-gland-specific protein

      Tomohiro Ueda, Hiroyuki Manabe, Keizo Tokuhiro, Mika Hirose, Yasuhiro Matsuoka, Yasushi Miyagawa, Akira Tsujimura, Kyoko Fujita, Morimasa Wada, Akihiko Okuyama, Yoshitake Nishimune and Hiromitsu Tanaka
      International Journal of Urology, 2009 16(7); 639-646

      The CXCL12 (SDF-1)/CXCR4 Axis Is Essential for the Development of Renal Vasculature

      Yoshitsugu Takabatake, Tatsuki Sugiyama, Hiroshi Kohara, Taiji Matsusaka, Hidetake Kurihara, Pandelakis A. Koni, Yasuyuki Nagasawa, Takayuki Hamano, Isao Matsui, Noritaka Kawada, Enyu Imai, Takashi Nagasawa, Hiromi Rakugi, and Yoshitaka Isaka
      Journal of the American Society of Nephrology, 2009 20(8); 1714-1723

      The Death Effector Domain-containing DEDD Supports S6K1 Activity via Preventing Cdk1-dependent Inhibitory Phosphorylation

      Nobuya Kurabe, Satoko Arai, Akemi Nishijima, Naoto Kubota, Futoshi Suizu, Mayumi Mori, Jun Kurokawa, Miki Kondo-Miyazaki, Tomohiro Ide, Kouji Murakami, Katsuhisa Miyake, Kohjiro Ueki, Hisashi Koga, Yutaka Yatomi, Fumio Tashiro, Masayuki Noguchi, Takashi Kadowaki, and Toru Miyazaki
      The Journal of Biological Chemistry, 2009 284(8); 5050-5055

      Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95

      Jun Noritake, Yuko Fukata, Tsuyoshi Iwanaga, Naoki Hosomi, Ryouhei Tsutsumi, Naoto Matsuda, Hideki Tani, Hiroko Iwanari, Yasuhiro Mochizuki, Tatsuhiko Kodama, Yoshiharu Matsuura, David S. Bredt, Takao Hamakubo, and Masaki Fukata

      The Journal of Cell Biology, 2009 186(1); 147-160

      Secretogranin II binds to secretogranin III and forms secretory granules with orexin, neuropeptide Y, and POMC

      Kikuko Hotta, Masahiro Hosaka, Atsushi Tanabe and Toshiyuki Takeuchi
      Journal of Endocrinology, 2009 202(1); 111-121

      Orengedokuto and berberine improve indomethacin-induced small intestinal injury via adenosine

      Yoko Watanabe-Fukuda, Masahiro Yamamoto, Naoko Miura, Masato Fukutake, Atsushi Ishige, Rui Yamaguchi, Masao Nagasaki, Ayumu Saito, Seiya Imoto, Satoru Miyano, Junzo Takeda, Kenji Watanabe
      Journal of Gastroenterology, 2009 44(5); 380-389

      Increased Hyaluronan Production and Decreased E-Cadherin Expression by Cytokine-Stimulated Keratinocytes Lead to Spongiosis Formation

      Tomoyuki Ohtani, Ai Memezawa, Ryuhei Okuyama, Tetsuya Sayo, Yoshinori Sugiyama, Shintaro Inoue and Setsuya Aiba
      Journal of Investigative Dermatology, 2009 129(6); 1412-1420

      The Modulation of MicroRNAs by Type I IFN through the Activation of Signal Transducers and Activators of Transcription 3 in Human Glioma

      Masasuke Ohno, Atsushi Natsume, Yutaka Kondo, Hidetaka Iwamizu, Kazuya Motomura, Hiroshi Toda, Motokazu Ito, Takenori Kato, and Toshihiko Wakabayashi
      Molecular Cancer Research, 2009 7(12); 2022-2030

      Expression of synemin in the mouse spinal cord

      Yuji Mizuno, Jeffrey R. Guyon, Koichi Okamoto, and Louis M. Kunkel
      Muscle & Nerve, 2009 39(5); 634-641

      Uptake through glycoprotein 2 of FimH+ bacteria by M cells initiates mucosal immune response

      Koji Hase, Kazuya Kawano, Tomonori Nochi, Gemilson Soares Pontes, Shinji Fukuda, Masashi Ebisawa, Kazunori Kadokura, Toru Tobe, Yumiko Fujimura, Sayaka Kawano, Atsuko Yabashi, Satoshi Waguri, Gaku Nakato, Shunsuke Kimura, Takaya Murakami, Mitsutoshi Iimura, Kimiyo Hamura, Shin-Ichi Fukuoka, Anson W. Lowe, Kikuji Itoh, Hiroshi Kiyono and Hiroshi Ohno
      Nature, 2009 462(7270); 226-231

      Lipopolysaccharides stimulate adrenomedullin synthesis in intestinal epithelial cells: Release kinetics and secretion polarity

      Hiroshi Kishikawa, Jiro Nishida, Hitoshi Ichikawa, Shogo Kaida, Tetsuo Morishita, Soichiro Miura, Toshifumi Hibi
      Peptides, 2009 30(5); 906-912

      Identification of a Novel Uromodulin-Like Gene Related to Predator-Induced Bulgy Morph in Anuran Tadpoles by Functional Microarray Analysis

      Tsukasa Mori, Hiroko Kawachi, Chiharu Imai, Manabu Sugiyama, Youichi Kurata, Osamu Kishida, Kinya Nishimura
      PLoS ONE, 2009 4(6); e5936

      TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cells

      Katsura Nozawa, Eri Kawabata-Shoda, Hitoshi Doihara, Ryosuke Kojima, Hidetsugu Okada, Shinobu Mochizuki, Yorikata Sano, Kohei Inamura, Hitoshi Matsushime, Tomonobu Koizumi, Toshihide Yokoyama, and Hiroyuki Ito
      Proceedings of the National Academy of Sciences of the USA, 2009 106(9); 3408-3413

      IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain

      Makoto Tsuda, Takahiro Masuda, Junko Kitano, Hiroshi Shimoyama, Hidetoshi Tozaki-Saitoh, and Kazuhide Inoue
      Proceedings of the National Academy of Sciences of the USA, 2009 106(19); 8032-8037


      【2008】

      Dehydration-inducible changes in expression of two aquaporins in the sleeping chironomid, Polypedilum vanderplanki

      Takahiro Kikawada, Ayako Saito, Yasushi Kanamori, Mika Fujita, Katarzyna Śnigórska, Masahiko Watanabe, Takashi Okuda
      Biochimica et Biophysica Acta, 2008 1778(2); 514-520

      DNA Hypomethylation Circuit of the Mouse Oocyte-Specific Histone H1foo Gene in Female Germ Cell Lineage

      Chiaki Maeda, Shun Sato, Naoko Hattori, Satoshi Tanaka, Shintaro Yagi, and Kunio Shiota
      Biology of Reproduction, 2008 78(5); 816-821

      Gene cloning and biochemical characterization of the BMP-2 of Pinctada fucata

      Tomoyuki Miyashita, Takuo Hanashita, Michinori Toriyama, Ryousuke Takagi, Tamaki Akashika, Nobuto Higashikubo
      Bioscience, Biotechnology, and Biochemistry, 2008 72(1); 37-47

      Annotated ESTs from various tissues of the brown planthopper Nilaparvata lugens : A genomic resource for studying agricultural pests

      Hiroaki Noda, Sawako Kawai, Yoko Koizumi, Kageaki Matsui, Qiang Zhang, Shigetoyo Furukawa, Michihiko Shimomura and Kazuei Mita
      BMC Genomics, 2008 9; 117

      Glutamine synthetase gene expression during the regeneration of the annelid Enchytraeus japonensis

      Cintia Carla Niva, Jae Min Lee and Maroko Myohara
      Development Genes and Evolution, 2008 218(1); 39-46

      Expression Profiling of PBMC-based Diagnostic Gene Markers Isolated from Vasculitis Patients

      Shigeto Kobayashi, Akihiko Ito, Daisuke Okuzaki, Hiroaki Onda, Norikazu Yabuta, Ippei Nagamori, Kazuo Suzuki, Hiroshi Hashimoto, and Hiroshi Nojima
      DNA Research, 2008 15(4); 253-265

      Involvement of Cytokine-Induced Neutrophil Chemoattractant in Hypothalamic Thermoregulation of Luteinizing Hormone-Releasing Hormone

      Masamichi Noguchi, Mitsutoshi Yuzurihara, Yoshio Kase, Toshiyuki Yasui, and Minoru Irahara
      Endocrinology, 2008 149(6); 2899-2906

      R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling

      Kazuma Tomizuka, Kaori Horikoshi, Rina Kitada, Yuriko Sugawara, Yumi Iba, Ayako Kojima, Akiko Yoshitome, Kengo Yamawaki, Mikiko Amagai, Ayano Inoue, Takeshi Oshima and Makoto Kakitani
      Human Molecular Genetics, 2008 17(9); 1278-1291

      Comparative expression analysis uncovers novel features of endogenous antisense transcription

      Yuki Okada, Chiaki Tashiro, Koji Numata, Kazufumi Watanabe, Hajime Nakaoka, Naoyuki Yamamoto, Kazue Okubo, Rieko Ikeda, Rintaro Saito, Akio Kanai, Kuniya Abe, Masaru Tomita and Hidenori Kiyosawa
      Human Molecular Genetics, 2008 17(11); 1631-1640

      Hemoglobin Is Expressed by Mesangial Cells and Reduces Oxidant Stress

      Hiroshi Nishi, Reiko Inagi, Hideki Kato, Masayuki Tanemoto, Ichiro Kojima, Daisuke Son, Toshiro Fujita, and Masaomi Nangaku
      Journal of the American Society of Nephrology, 2008 19(8); 1500-1508

      Pancreatic Endocrine and Exocrine Cell Ontogeny From Renal Capsule-transplanted Embryonic Stem Cells in Streptozocin-injured Mice

      Maho Kodama, Fumitaka Takeshita, Shiro Kanegasaki, Takahiro Ochiya, and Gary Quinn
      Journal of Histochemistry & Cytochemistry, 2008 56(1); 33-44

      Comprehensive Gene Expression Profiling of Peyer’s Patch M Cells, Villous M-Like Cells, and Intestinal Epithelial Cells

      Kazutaka Terahara, Masato Yoshida, Osamu Igarashi, Tomonori Nochi, Gemilson Soares Pontes, Koji Hase, Hiroshi Ohno, Shiho Kurokawa, Mio Mejima, Naoko Takayama, Yoshikazu Yuki, Anson W. Lowe, and Hiroshi Kiyono
      The Journal of Immunology, 2008 180(12); 7840-7846

      P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury

      Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Hiroyuki Miyata, Kazuaki Ueda, Shinichi Kohsaka, and Kazuhide Inoue
      The Journal of Neuroscience, 2008 28(19); 4949-4956

      Neoculin, a taste-modifying sweet protein, accumulates inripening fruits of cultivated Curculigo latifolia

      Satoshi Okubo, Tomiko Asakura, Kazue Okubo, Kazutoshi Abe, Takumi Misaka, Toru Akita, Keiko Abe
      Journal of Plant Physiology, 2008 165(18); 1964-1969

      Involvement of Mos-MEK-MAPK pathway in cytostatic factor (CSF) arrest in eggs of the parthenogenetic insect, Athalia rosae

      Daisuke S. Yamamoto, Kazunori Tachibana, Megumi Sumitani, Jae Min Lee, Masatsugu Hatakeyama
      Mechanisms of Development, 2008 125(11-12); 996-1008

      The Zinc Transporter SLC39A13/ZIP13 Is Required for Connective Tissue Development; Its Involvement in BMP/TGF-β Signaling Pathways

      Toshiyuki Fukada, Natacha Civic, Tatsuya Furuichi, Shinji Shimoda, Kenji Mishima, Hiroyuki Higashiyama, Yayoi Idaira, Yoshinobu Asada, Hiroshi Kitamura, Satoru Yamasaki, Shintaro Hojyo, Manabu Nakayama, Osamu Ohara, Haruhiko Koseki, Heloisa G. dos Santos, Luisa Bonafe, Russia Ha-Vinh, Andreas Zankl, Sheila Unger, Marius E. Kraenzlin, Jacques S. Beckmann, Ichiro Saito, Carlo Rivolta, Shiro Ikegawa, Andrea Superti-Furga, Toshio Hirano
      PLoS ONE, 2008 3(11); e3642

      Gene expression profiles in the articular cartilage of juvenile rats receiving the quinolone antibacterial agent ofloxacin

      Koichi Goto, Koichi Yabe, Takami Suzuki, Kiyoshi Takasuna, Toshimasa Jindo, Sunao Manabe
      Toxicology, 2008 249(2-3); 204-213


      【2007】

      Identification and characterization of the human SOX6 promoter

      Toshiyuki Ikeda, Taku Saito, Masahiro Ushita, Fumiko Yano, Akinori Kan, Keiji Itaka, Toru Moro, Kozo Nakamura, Hiroshi Kawaguchi, Ung-il Chung
      Biochemical and Biophysical Research Communications, 2007 357(2); 383-390

      PPARα Agonists Positively and Negatively Regulate the Expression of Several Nutrient/Drug Transporters in Mouse Small Intestine

      Toshitake Hirai, Yuka Fukui, and Kiyoto Motojima
      Biological and Pharmaceutical Bulletin, 2007 30(11); 2185-2190

      Orally administered lactoperoxidase increases expression of the FK506 binding protein 5 gene in epithelial cells of the small intestine of mice: a DNA microarray study

      Hiroyuki Wakabayashi, Hirofumi Miyauchi, Kouichirou Shin, Koji Yamauchi, Ichiro Matsumoto, Keiko Abe, and Mitsunori Takase
      Bioscience, Biotechnology, and Biochemistry, 2007 71(9); 2271-2282

      Psg18 is specifically expressed in follicle-associated epithelium

      Kazuya Kawano, Masashi Ebisawa, Koji Hase, Shinji Fukuda, Atsushi Hijikata, Sayaka Kawano, Yasuhiro Date, Satoshi Tsuneda, Kikuji Itoh, and Hiroshi Ohno
      Cell Structure and Function, 2007 32(2); 115-126

      MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation

      Emiko Suzuki, Manabu Nakayama
      Experimental Cell Research, 2007 313(17); 3729-3742

      Ammonia secretion from fish gill depends on a set of Rh glycoproteins

      Tsutomu Nakada, Connie M. Westhoff, Akira Kato, and Shigehisa Hirose
      The FASEB Journal, 2007 21(4); 1067-1074

      Regulated expression by PPARα and unique localization of 17β-hydroxysteroid dehydrogenase type 11 protein in mouse intestine and liver

      Yasuhide Yokoi, Yuka Horiguchi, Makoto Araki and Kiyoto Motojima
      The FEBS Journal, 2007 274(18); 4837-4847

      Gene expression pattern of Cue110: A member of the uncharacterized UPF0224 gene family preferentially expressed in germ cells

      Takuji Yoshimura, Tatsushi Miyazaki, Shuichi Toyoda, Satsuki Miyazaki, Fumi Tashiro, Eiji Yamato, Jun-ichi Miyazaki
      Gene Expression Patterns, 2007 8(1); 27-35

      A new class of tissue-specifically methylated regions involving entire CpG islands in the mouse

      Masako Suzuki, Shun Sato, Yoshikazu Arai, Takashi Shinohara, Satoshi Tanaka, John M. Greally, Naka Hattori and Kunio Shiota
      Genes to Cells, 2007 12(12); 1305-1314

      Fine mapping of a swine quantitative trait locus for number of vertebrae and analysis of an orphan nuclear receptor, germ cell nuclear factor (NR6A1)

      Satoshi Mikawa, Takeya Morozumi, Shin-Ichi Shimanuki, Takeshi Hayashi, Hirohide Uenishi, Michiko Domukai, Naohiko Okumura, and Takashi Awata
      Genome Research, 2007 17(5); 586-593

      Association of single-nucleotide polymorphisms in MTMR9 gene with obesity

      Takahiro Yanagiya, Atsushi Tanabe, Aritoshi Iida, Susumu Saito, Akihiro Sekine, Atsushi Takahashi, Tatsuhiko Tsunoda, Seika Kamohara, Yoshio Nakata, Kazuaki Kotani, Ryoya Komatsu, Naoto Itoh, Ikuo Mineo, Jun Wada, Hiroaki Masuzaki, Masato Yoneda, Atsushi Nakajima, Shigeru Miyazaki, Katsuto Tokunaga, Manabu Kawamoto, Tohru Funahashi, Kazuyuki Hamaguchi, Kiyoji Tanaka, Kentaro Yamada, Toshiaki Hanafusa, Shinichi Oikawa, Hironobu Yoshimatsu, Kazuwa Nakao, Toshiie Sakata, Yuji Matsuzawa, Naoyuki Kamatani, Yusuke Nakamura and Kikuko Hotta
      Human Molecular Genetics, 2007 16(24); 3017-3026

      Expression and Regulation of the Osteoarthritis-associated Protein Asporin

      Ikuyo Kou, Masahiro Nakajima, and Shiro Ikegawa
      The Journal of Biological Chemistry, 2007 282(44); 32193-32199

      Functional Single-Nucleotide Polymorphisms in the Secretogranin III (SCG3) Gene that Form Secretory Granules with Appetite-Related Neuropeptides Are Associated with Obesity

      Atsushi Tanabe, Takahiro Yanagiya, Aritoshi Iida, Susumu Saito, Akihiro Sekine, Atsushi Takahashi, Takahiro Nakamura, Tatsuhiko Tsunoda, Seika Kamohara, Yoshio Nakata, Kazuaki Kotani, Ryoya Komatsu, Naoto Itoh, Ikuo Mineo, Jun Wada, Tohru Funahashi, Shigeru Miyazaki, Katsuto Tokunaga, Kazuyuki Hamaguchi, Tatsuo Shimada, Kiyoji Tanaka, Kentaro Yamada, Toshiaki Hanafusa, Shinichi Oikawa, Hironobu Yoshimatsu, Toshiie Sakata, Yuji Matsuzawa, Naoyuki Kamatani, Yusuke Nakamura, and Kikuko Hotta
      The Journal of Clinical Endocrinology & Metabolism, 2007 92(3); 1145-1154

      A Local Reduction in Cortical GABAergic Synapses after a Loss of Endogenous Brain-Derived Neurotrophic Factor, as Revealed by Single-Cell Gene Knock-Out Method

      Keigo Kohara, Hiroki Yasuda, Yan Huang, Naoki Adachi, Kazuhiro Sohya, and Tadaharu Tsumoto
      The Journal of Neuroscience, 2007 27(27); 7234 -7244

      Synemin Expression in Brain

      Yuji Mizuno, Jeffrey R. Guyon, Koichi Okamoto, and Louis M. Kunkel
      Muscle & Nerve, 2007 36(4); 497-504

      UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis

      Schuichi Koizumi, Yukari Shigemoto-Mogami, Kaoru Nasu-Tada, Yoichi Shinozaki, Keiko Ohsawa, Makoto Tsuda, Bhalchandra V. Joshi, Kenneth A. Jacobson, Shinichi Kohsaka and Kazuhide Inoue
      Nature, 2007 446(7139); 1091-1095

      Regulation of Dendritogenesis via a Lipid-Raft-Associated Ca2+/Calmodulin-Dependent Protein Kinase CLICK-III/CaMKIg

      Sayaka Takemoto-Kimura, Natsumi Ageta-Ishihara, Mio Nonaka, Aki Adachi-Morishima, Tatsuo Mano, Michiko Okamura, Hajime Fujii, Toshimitsu Fuse, Mikio Hoshino, Shingo Suzuki, Masami Kojima, Masayoshi Mishina, Hiroyuki Okuno, and Haruhiko Bito
      Neuron, 2007 54(5); 755-770

      Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination

      Tomonori Nochi, Hidenori Takagi, Yoshikazu Yuki, Lijun Yang, Takehiro Masumura, Mio Mejima, Ushio Nakanishi, Akiko Matsumura, Akihiro Uozumi, Takachika Hiroi, Shigeto Morita, Kunisuke Tanaka, Fumio Takaiwa, and Hiroshi Kiyono

      Proceedings of the National Academy of Sciences of the USA, 2007 104(26); 10986-10991

      Trehalose transporter 1, a facilitated and high-capacity trehalose transporter, allows exogenous trehalose uptake into cells

      Takahiro Kikawada, Ayako Saito, Yasushi Kanamori, Yuichi Nakahara, Ken-ichi Iwata, Daisuke Tanaka, Masahiko Watanabe, and Takashi Okuda
      Proceedings of the National Academy of Sciences of the USA, 2007 104(28); 11585-11590


      【2006】

      Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine

      Masumi Takano-Maruyama, Koji Hase, Hiroshi Fukamachi, Yasutaka Kato, Haruhiko Koseki, and Hiroshi Ohno
      American Journal of Physiology – Gastrointestinal and Liver Physiology, 2006 291(1); G163-G170

      Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases

      Hirofumi Shoda, Keishi Fujio, Yumi Yamaguchi, Akiko Okamoto, Tetsuji Sawada, Yuta Kochi and Kazuhiko Yamamoto
      Arthritis Research & Therapy, 2006 8(6); R166

      Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: Predominant localization in pancreatic polypeptide-secreting PP-cells

      Yukiko Sakamoto, Hiroshi Inoue, Shuhei Kawakami, Katsuyuki Miyawaki, Tatsuro Miyamoto, Kuniko Mizuta, Mitsuo Itakura
      Biochemical and Biophysical Research Communications, 2006 351(2); 474-480

      Unique Distribution of Thrombospondin-1 in Human Ocular Surface Epithelium

      Eiichi Sekiyama, Takahiro Nakamura, Leanne J. Cooper, Satoshi Kawasaki, Junji Hamuro, Nigel J. Fullwood, and Shigeru Kinoshita
      Investigative Ophthalmology & Visual Science, 2006 47(4); 1352-1358

      Molecular Identification and Characterization of a Family of Kinases with Homology to Ca2+/Calmodulin-dependent Protein Kinases I/IV

      Shogo Ohmae, Sayaka Takemoto-Kimura, Michiko Okamura, Aki Adachi-Morishima, Mio Nonaka, Toshimitsu Fuse, Satoshi Kida, Masahiro Tanji, Tomoyuki Furuyashiki, Yoshiki Arakawa, Shuh Narumiya, Hiroyuki Okuno, and Haruhiko Bito
      The Journal of Biological Chemistry, 2006 281(29); 20427-20439

      cDNA cloning and in situ hybridization of Δ11-desaturase, a key enzyme of pheromone biosynthesis in Ostrinia scapulalis (Lepidoptera: Crambidae)

      Mai Fukuzawa, Xiaoyan Fu, Sadahiro Tatsuki, Yukio Ishikawa
      Journal of Insect Physiology, 2006 52(5); 430-435

      Inhibition of D-serine accumulation in the Xenopus oocyte by expression of the rat ortholog of human 3′-phosphoadenosine 5′-phosphosulfate transporter gene isolated from the neocortex as D-serine modulator-1

      Dai Shimazu, Naoki Yamamoto, Asami Umino, Sumikazu Ishii, Shin-ichiro Sakurai and Toru Nishikawa
      Journal of Neurochemistry, 2006 96(1); 30-42

      Disruption of Spermatogenic Cell Adhesion and Male Infertility in Mice Lacking TSLC1/IGSF4, an Immunoglobulin Superfamily Cell Adhesion Molecule

      Daisuke Yamada, Midori Yoshida, Yuko N. Williams, Takeshi Fukami, Shinji Kikuchi, Mari Masuda, Tomoko Maruyama, Tsutomu Ohta, Dai Nakae, Akihiko Maekawa, Tadaichi Kitamura, and Yoshinori Murakami
      Molecular and Cellular Biology, 2006 26(9); 3610-3624

      Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

      Seiji Okada, Masaya Nakamura, Hiroyuki Katoh, Tamaki Miyao, Takuya Shimazaki, Ken Ishii, Junichi Yamane, Akihiko Yoshimura, Yukihide Iwamoto, Yoshiaki Toyama and Hideyuki Okano
      Nature Medicine, 2006 12(7); 829-834


      【2005】

      Roles of Slc13a1 and Slc26a1 sulfate transporters of eel kidney in sulfate homeostasis and osmoregulation in freshwater

      Tsutomu Nakada, Kambiz Zandi-Nejad, Yukihiro Kurita, Hisayuki Kudo, Vadjista Broumand, Charles Y. Kwon, Adriana Mercado, David B. Mount, and Shigehisa Hirose
      American Journal of Physiology – Regulatory, Integrative and Comparative Physiology, 2005 289(2); R575-R585

      A novel type of urea transporter, UT-C, is highly expressed in proximal tubule of seawater eel kidney

      Abinash Chandra Mistry, Guangping Chen, Akira Kato, Kakon Nag, Jeff M. Sands, and Shigehisa Hirose
      American Journal of Physiology – Renal Physiology, 2005 288(3); F455-F465

      A Novel Phospholipase C, PLCη2, Is a Neuron-specific Isozyme

      Masamichi Nakahara, Makoto Shimozawa, Yoshikazu Nakamura, Yasuhiro Irino, Mitsuhiro Morita, Yoshihisa Kudo, and Kiyoko Fukami
      The Journal of Biological Chemistry, 2005 280(32); 29128-29134

      Cutting Edge: Critical Role of CXCL16/CXCR6 in NKT Cell Trafficking in Allograft Tolerance

      Xiaofeng Jiang, Takeshi Shimaoka, Satoshi Kojo, Michishige Harada, Hiroshi Watarai, Hiroshi Wakao, Nobuhiro Ohkohchi, Shin Yonehara, Masaru Taniguchi, and Ken-ichiro Seino
      The Journal of Immunology, 2005 175(4); 2051-2055

      Gene expression profile in rat pancreatic islet and RINm5F cells

      H Wang, Y Horikawa, L Jin, T Narita, S Yamada, N Shihara, K Tatemoto, M Muramatsu, T Mune and J Takeda
      Journal of Molecular Endocrinology, 2005 35(1): 1-12

      Down-regulation of a morphogen (sonic hedgehog) gradient in the gastric epithelium of Helicobacter pylori -infected Mongolian gerbils

      Hidekazu Suzuki, Yuriko Minegishi, Yohei Nomoto, Takayuki Ota, Tatsuhiro Masaoka, Gijs R van den Brink and Toshifumi Hibi
      Journal of Pathology, 2005 206(2); 186-197

      A functional variant in FcRH3, encoding Fc Receptor Homolog 3, is associated with rheumatoid arthritis and several autoimmunities

      Yuta Kochi, Ryo Yamada, Akira Suzuki, John B Harley, Senji Shirasawa, Tetsuji Sawada, Sang-Cheol Bae, Shinya Tokuhiro, Xiaotian Chang, Akihiro Sekine, Atsushi Takahashi, Tatsuhiko Tsunoda, Yozo Ohnishi, Kenneth M Kaufman, Changwon Kang, Shigeru Otsubo, Wako Yumura, Akio Mimori, Takao Koike, Yusuke Nakamura, Takehiko Sasazuki and Kazuhiko Yamamoto
      Nature Genetics, 2005 37(5); 478-485


      【2004】

      Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

      Kyoko Fujiwara, Masako Ochiai, Tsutomu Ohta, Misao Ohki, Hiroyuki Aburatani, Minako Nagao, Takashi, Sugimura and Hitoshi Nakagama
      Carcinogenesis, 2004 25(8); 1495-1505


      【2003】

      Identification of CRYM as a Candidate Responsible for Nonsyndromic Deafness, through cDNA Microarray Analysis of Human Cochlear and Vestibular Tissues

      Satoko Abe, Toyomasa Katagiri, Akihiko Saito-Hisaminato, Shin-ichi Usami, Yasuhiro Inoue, Tatsuhiko Tsunoda, and Yusuke Nakamura
      American Journal of Human Genetics, 2003 72(1); 73-82

      Non-cloning Synthesis of cRNA Probe and Its Application to In Situ Hybridization Analysis of Formalin-fixed Paraffin Embedded Tissue

      Kiyoshi Kobayashi, Hideki Tanaka, Maki Goda, and Atsushi Fukunari
      Journal of Toxicologic Pathology, 2003 16(4); 247-251


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